Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCB | P05771 | 8/20 | 0.44 |
| ▸ | PRKCA | P17252 | 3/20 | 0.44 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.44 |
| ▸ | CAMK2D | Q13557 | 2/20 | 0.44 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.44 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.44 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.44 |
| ▸ | ABL1 | P00519 | 1/20 | 0.44 |
| ▸ | PRKCG | P05129 | 1/20 | 0.44 |
| ▸ | CDK1 | P06493 | 1/20 | 0.44 |
| ▸ | PIM1 | P11309 | 1/20 | 0.44 |
| ▸ | CDK4 | P11802 | 1/20 | 0.44 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.44 |
| ▸ | PRKACA | P17612 | 1/20 | 0.44 |
| ▸ | PRKACG | P22612 | 1/20 | 0.44 |
| ▸ | PRKACB | P22694 | 1/20 | 0.44 |
| ▸ | CCND1 | P24385 | 1/20 | 0.44 |
| ▸ | PRKCH | P24723 | 1/20 | 0.44 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.44 |
| ▸ | CDK2 | P24941 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5329180 | 0.70 | KDR (0.55) | PRKCBPRKCASIRT2CAMK2DPRKD3 | |
| SCHEMBL6015859 | 0.70 | PDK2 (0.39) | — | |
| SCHEMBL4556996 | 0.68 | PTPRC (0.45) | PRKCBPRKCASIRT2CAMK2DPRKD3 | |
| SCHEMBL1202543 | 0.68 | IMPDH2 (0.63) | PRKCBPRKCASIRT2CAMK2DPRKD3 | |
| SCHEMBL6015962 | 0.68 | NTRK1 (0.62) | PRKCBPRKCASIRT2CAMK2DPRKD3 | |
| SCHEMBL10438759 | 0.66 | SIRT2 (0.58) | PRKCBPRKCASIRT2CAMK2DPRKD3 | |
| SCHEMBL18392162 | 0.65 | SIRT2 (0.61) | PRKCBPRKCASIRT2CAMK2DPRKD3 | |
| SCHEMBL4556994 | 0.65 | PTPRC (0.47) | PRKCBPRKCASIRT2CAMK2DPRKD3 | |
| SCHEMBL7198015 | 0.64 | SIRT2 (0.44) | PRKCBPRKCASIRT2CAMK2DPRKD3 | |
| SCHEMBL3291196 | 0.64 | ALDH1A1 (0.53) | PRKCBPRKCASIRT2CAMK2DPRKD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7049312-B1 | Benzothiazinone and benzoxazinone compounds | ABBOTT GMBH & CO. KG (DE) | 2006-05-23 | — | — | US | disclosed |
| EP-1181282-A2 | BENZOTHIAZINONE AND BENZOXAZINONE COMPOUNDS | BASF AKTIENGESELLSCHAFT (DE) | 2002-02-27 | — | — | EP | disclosed |
| WO-2000075139-A2 | BENZOTHIAZINONE AND BENZOXAZINONE COMPOUNDS | BASF AKTIENGESELLSCHAFT (DE) | 2000-12-14 | — | — | WO | disclosed |