Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | SCN1A | P35498 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | SYK | P43405 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16254583 | 0.71 | KDM5A (0.49) | MAPK1POLBSMN1; SMN2ALDH1A1CYP1A2 | |
| SCHEMBL6015760 | 0.67 | PKM (0.36) | POLBSMN1; SMN2ALDH1A1SIGMAR1HRH3 | |
| SCHEMBL6015852 | 0.67 | SMN1; SMN2 (0.41) | MAPK1POLBSMN1; SMN2ALDH1A1CYP1A2 | |
| SCHEMBL3258076 | 0.67 | LMNA (0.38) | MAPK1POLBALDH1A1CYP1A2CHRM2 | |
| SCHEMBL235080 | 0.66 | KDM4E (0.65) | POLBSMN1; SMN2ALDH1A1SIGMAR1HRH3 | |
| SCHEMBL17008888 | 0.66 | SMN1; SMN2 (0.46) | MAPK1SMN1; SMN2ALDH1A1CYP1A2CHRM2 | |
| SCHEMBL10247439 | 0.64 | HTR2A (0.51) | MAPK1POLBALDH1A1CYP1A2CHRM2 | |
| SCHEMBL14553277 | 0.64 | ALDH1A1 (0.51) | MAPK1POLBSMN1; SMN2ALDH1A1CYP1A2 | |
| SCHEMBL19732396 | 0.64 | FLT3 (0.49) | MAPK1POLBSMN1; SMN2ALDH1A1SIGMAR1 | |
| SCHEMBL10913328 | 0.63 | KDM4E (0.70) | POLBSMN1; SMN2ALDH1A1SIGMAR1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7049312-B1 | Benzothiazinone and benzoxazinone compounds | ABBOTT GMBH & CO. KG (DE) | 2006-05-23 | — | — | US | claimed |
| EP-1181282-A2 | BENZOTHIAZINONE AND BENZOXAZINONE COMPOUNDS | BASF AKTIENGESELLSCHAFT (DE) | 2002-02-27 | — | — | EP | claimed |
| WO-2000075139-A2 | BENZOTHIAZINONE AND BENZOXAZINONE COMPOUNDS | BASF AKTIENGESELLSCHAFT (DE) | 2000-12-14 | — | — | WO | claimed |
| US-7049312-B1 | Benzothiazinone and benzoxazinone compounds | ABBOTT GMBH & CO. KG (DE) | 2006-05-23 | — | — | US | disclosed |