Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 17/20 | 0.56 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | HRH1 | P35367 | 1/20 | 0.49 |
| ▸ | HTR3A | P46098 | 1/20 | 0.43 |
| ▸ | RHEB | Q15382 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL523253 | 0.83 | RHEB (0.54) | HRH4HRH3RHEB | |
| SCHEMBL602043 | 0.81 | HRH4 (0.81) | HRH4HRH3ALOX15HRH1 | |
| SCHEMBL6016849 | 0.79 | HRH4 (0.64) | HRH4HRH3ALOX15HRH1 | |
| Maleic Acid SCHEMBL602941 | 0.78 | ALOX15 (0.84) | HRH4HRH3ALOX15HRH1 | |
| Maleic Acid SCHEMBL20162482 | 0.78 | ALOX15 (0.84) | HRH4HRH3ALOX15HRH1 | |
| Maleic Acid SCHEMBL29404707 | 0.78 | ALOX15 (0.84) | HRH4HRH3ALOX15HRH1 | |
| Fumaric Acid SCHEMBL602943 | 0.78 | ALOX15 (0.84) | HRH4HRH3ALOX15HRH1 | |
| SCHEMBL605331 | 0.77 | HRH4 (0.59) | HRH4HRH3ALOX15HRH1 | |
| Jnj-7777120 SCHEMBL18486196 | 0.75 | HRH4 (0.80) | HRH4HRH3ALOX15HRH1 | |
| SCHEMBL25812917 | 0.74 | HRH4 (0.48) | HRH4HRH3ALOX15RHEB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1636216-A1 | BENZIMIDAZOLE-DERIVATIVES AS FACTOR Xa INHIBITORS | Sanofi-Aventis Deutschland GmbH (DE) | 2006-03-22 | — | — | EP | disclosed |
| WO-2004101553-A1 | BENZIMIDAZOLE-DERIVATIVES AS FACTOR Xa INHIBITORS | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2004-11-25 | — | — | WO | disclosed |