Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK9 | P45984 | 5/20 | 0.40 |
| ▸ | MAPK10 | P53779 | 5/20 | 0.40 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.34 |
| ▸ | CSF1R | P07333 | 1/20 | 0.33 |
| ▸ | NR1D1 | P20393 | 1/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.33 |
| ▸ | MTOR | P42345 | 1/20 | 0.33 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.33 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4020855 | 0.70 | MAPK10 (0.76) | MAPK9MAPK10MAPK8RAB9AMAPT | |
| SCHEMBL3742492 | 0.68 | MAPK10 (0.71) | MAPK9MAPK10MAPK8RAB9ACYP11B1 | |
| SCHEMBL2883226 | 0.66 | MAPK10 (0.83) | MAPK9MAPK10MAPK8RAB9ACSF1R | |
| SCHEMBL4026695 | 0.66 | MAPK10 (0.81) | MAPK9MAPK10MAPK8RAB9APIK3CA | |
| SCHEMBL7707034 | 0.64 | MAPK10 (0.45) | MAPK9MAPK10MAPK8RAB9AMTOR | |
| SCHEMBL7707461 | 0.63 | CYP11B1 (0.36) | RAB9ACYP11B1CYP11B2MAPTLMNA | |
| SCHEMBL5566249 | 0.62 | MAPK10 (0.45) | MAPK9MAPK10MAPK8RAB9AMKNK1 | |
| SCHEMBL6017675 | 0.61 | MAPK10 (0.44) | MAPK9MAPK10MAPK8RAB9AMKNK1 | |
| SCHEMBL4020757 | 0.60 | MAPK10 (0.76) | MAPK9MAPK10MAPK8RAB9APIK3CA | |
| SCHEMBL4203402 | 0.59 | RAB9A (0.43) | MAPK9MAPK10RAB9AMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1696909-A1 | BENZOTHIAZOLE DERIVATIVES FOR THE TREATMENT OF DIABETES | Applied Research Systems ARS Holding N.V. (AN) | 2006-09-06 | — | — | EP | disclosed |
| WO-2005025567-A1 | BENZOTHIAZOLE DERIVATIVES FOR THE TREATMENT OF DIABETES | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 2005-03-24 | — | — | WO | disclosed |