Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 2/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.36 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.31 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 3/20 | 0.30 |
| ▸ | MAPT | P10636 | 3/20 | 0.30 |
| ▸ | MEN1 | O00255 | 2/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | RET | P07949 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | HTR1A | P08908 | 1/20 | 0.30 |
| ▸ | DRD2 | P14416 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4197970 | 0.82 | GPX4 (0.35) | LMNAMAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL4203402 | 0.82 | RAB9A (0.43) | PDE10ALMNAMAPTMEN1KMT2A | |
| SCHEMBL7707665 | 0.81 | NAAA (0.39) | CYP11B1CYP11B2PDE10ALMNAMAPT | |
| SCHEMBL5613944 | 0.80 | MAPK8 (0.38) | CYP11B1CYP11B2CYP19A1LMNAMEN1 | |
| SCHEMBL4192595 | 0.80 | MAPK9 (0.36) | LMNAMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL7707025 | 0.79 | NAAA (0.32) | LMNAMAPTMEN1KMT2ARAB9A | |
| SCHEMBL7707443 | 0.79 | RAB9A (0.44) | LMNAMAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL4192500 | 0.78 | NAAA (0.42) | PDE10ALMNAMAPTALDH1A1RAB9A | |
| SCHEMBL7710188 | 0.77 | LMNA (0.40) | LMNAMAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL4190547 | 0.74 | MAPK9 (0.39) | LMNAMAPTMEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1240164-A1 | BENZAZOLE DERIVATIVES AND THEIR USE AS JNK MODULATORS | Applied Research Systems ARS Holding N.V. (AN) | 2002-09-18 | — | — | EP | claimed |
| WO-2001047920-A1 | BENZAZOLE DERIVATIVES AND THEIR USE AS JNK MODULATORS | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 2001-07-05 | — | — | WO | claimed |