Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 12/20 | 0.59 |
| ▸ | NAAA | Q02083 | 1/20 | 0.50 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.39 |
| ▸ | HRH2 | P25021 | 2/20 | 0.39 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29263696 | 1.00 | HRH1 (0.59) | HRH1NAAAMAOAMAPTHRH3 | |
| SCHEMBL1532281 | 0.90 | HRH1 (0.47) | HRH1NAAAMAOAHRH3HRH4 | |
| Hydrochloric Acid SCHEMBL21000997 | 0.88 | HRH1 (0.45) | HRH1NAAAMAOAHRH3HRH4 | |
| SCHEMBL7453122 | 0.81 | DNM1 (0.50) | HRH1 | |
| SCHEMBL19078890 | 0.80 | HRH1 (0.49) | HRH1NAAAMAOAHRH3HRH2 | |
| SCHEMBL1086870 | 0.79 | — | — | |
| SCHEMBL6017591 | 0.79 | HRH1 (0.47) | HRH1MAOAHRH3HRH2HRH4 | |
| SCHEMBL16269873 | 0.79 | HRH1 (0.43) | HRH1NAAAMAOAHRH3HRH2 | |
| SCHEMBL9706426 | 0.78 | NAAA (0.52) | HRH1NAAA | |
| Hydrochloric Acid SCHEMBL3888095 | 0.77 | HRH1 (0.50) | HRH1NAAAMAPTHRH3HRH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004035764-A2 | PROTEIN SYNTHESIS WITH TANDEMLY ACTIVATED tRNAs | UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) | 2004-04-29 | — | — | WO | disclosed |
| US-6706215-B1 | 2-(2'-HYDROXYPHENYL)-1,3-PYRIMIDINE DERIVATIVE | CIBA SPECIALTY CHEMICALS CORPORATION | 2004-03-16 | — | — | US | disclosed |
| US-5753729-A | COATING COMPOSITION COMPRISING ORGANIC POLYMER BINDER, 2-(2*-HYDROXYPHENYL)PYRIMIDINE STABILIZER | CIBA SPECIALTY CHEMICALS CORPORATION | 1998-05-19 | — | — | US | disclosed |
| US-3950525-A | BRONCHODILATION, 4-HYDROXY-6-ARYL PYRIMIDINES | PFIZER INC. (US) | 1976-04-13 | — | — | US | disclosed |