Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | F2 | P00734 | 2/20 | 0.32 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.32 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.32 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL418256 | 1.00 | ALDH1A1 (0.33) | ALDH1A1F2PRSS1PRSS2PRSS3 | |
| SCHEMBL7559620 | 0.98 | F2 (0.33) | ALDH1A1F2PRSS1PRSS2PRSS3 | |
| SCHEMBL9136368 | 0.88 | DGAT1 (0.34) | ALDH1A1 | |
| SCHEMBL12658242 | 0.88 | DGAT1 (0.34) | ALDH1A1 | |
| SCHEMBL416924 | 0.86 | ALDH1A1 (0.35) | ALDH1A1 | |
| SCHEMBL7258369 | 0.86 | ALDH1A1 (0.35) | ALDH1A1 | |
| SCHEMBL421215 | 0.86 | ALDH1A1 (0.35) | ALDH1A1 | |
| SCHEMBL11938228 | 0.85 | DGAT1 (0.36) | ALDH1A1 | |
| SCHEMBL7558556 | 0.85 | ALDH1A1 (0.31) | ALDH1A1F2PRSS1PRSS2PRSS3 | |
| SCHEMBL20560996 | 0.84 | THRB (0.32) | ALDH1A1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7090829-B2 | Antitumor agnets; anticancer agents; antidiabetic agents | CARBOMER, INC. (US) | 2006-08-15 | — | — | US | disclosed |
| WO-2003086474-A2 | FLUORINATED OR PARAMAGNETIC ALGINATE POLYMER, ANNEXIN PARAMAGNETIC CONJUGATE, AND THEIR USE AS CONTRASTING AGENT IN MRI | CARBOMER, INC (US) | 2003-10-23 | — | — | WO | disclosed |
| US-20030198599-A1 | Novel imaging probes | CARBOMER, INC. | 2003-10-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030198599-A1 | Novel imaging probes | MPI, MIA3, PITPNB | ALDH1A1 3450/4885F2 2007/4885PRSS1 2217/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.