SCHEMBL418256

SCHEMBL418256

COC(=O)C(F)(F)OC(F)(F)C(F)(F)OC(F)(F)C(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.33

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.33
F2 P00734 2/20 0.32
PRSS1 P07477 2/20 0.32
PRSS2 P07478 2/20 0.32
PRSS3 P35030 2/20 0.32
THRB P10828 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6017763 1.00 ALDH1A1 (0.33) ALDH1A1F2PRSS1PRSS2PRSS3
SCHEMBL7559620 0.98 F2 (0.33) ALDH1A1F2PRSS1PRSS2PRSS3
SCHEMBL9136368 0.88 DGAT1 (0.34) ALDH1A1
SCHEMBL12658242 0.88 DGAT1 (0.34) ALDH1A1
SCHEMBL416924 0.86 ALDH1A1 (0.35) ALDH1A1
SCHEMBL7258369 0.86 ALDH1A1 (0.35) ALDH1A1
SCHEMBL421215 0.86 ALDH1A1 (0.35) ALDH1A1
SCHEMBL11938228 0.85 DGAT1 (0.36) ALDH1A1
SCHEMBL7558556 0.85 ALDH1A1 (0.31) ALDH1A1F2PRSS1PRSS2PRSS3
SCHEMBL20560996 0.84 THRB (0.32) ALDH1A1THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9117475-B2 Lubricant composition and use thereof FUJIFILM CORPORATION (JP) 2015-08-25 US disclosed
EP-2412789-A1 LUBRICANT COMPOSITION AND USE THEREOF FUJIFILM Corporation (JP) 2012-02-01 EP disclosed
US-20120021253-A1 LUBRICANT COMPOSITION AND USE THEREOF FUJIFILM CORPORATION (JP) 2012-01-26 US disclosed
EP-0868477-B1 FLUORINATED ONIUM SALTS, CURABLE COMPOSITIONS CONTAINING SAME, AND METHOD OF CURING USING SAME MINNESOTA MINING & MFG (US) 2004-08-11 EP disclosed
EP-0638112-B1 LIQUID CRYSTAL COMPOUNDS HAVING PERFLUOROETHER TERMINAL PORTIONS MINNESOTA MINING & MFG (US) 2002-08-07 EP disclosed
EP-0792255-B1 LIQUID CRYSTAL COMPOUNDS HAVING PERFLUOROETHER TERMINAL PORTIONS MINNESOTA MINING & MFG (US) 2001-02-28 EP disclosed
EP-0868477-A1 FLUORINATED ONIUM SALTS, CURABLE COMPOSITIONS CONTAINING SAME, AND METHOD OF CURING USING SAME MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1998-10-07 EP disclosed
EP-0736078-B1 CHIRAL LIQUID CRYSTAL COMPOUNDS HAVING A PERFLUOROETHER TERMINAL PORTION MINNESOTA MINING & MFG (US) 1998-06-24 EP disclosed
US-5734085-A RELEASE AGENT FOR FLUOROPOLYMERS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1998-03-31 US disclosed
EP-0792255-A1 LIQUID CRYSTAL COMPOUNDS HAVING PERFLUOROETHER TERMINAL PORTIONS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1997-09-03 EP disclosed
WO-1995017481-A1 CHIRAL LIQUID CRYSTAL COMPOUNDS HAVING A PERFLUOROETHER TERMINAL PORTION MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1995-06-29 WO disclosed
US-5399718-A Direct fluorination process for making perfluorinated organic substances MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1995-03-21 US disclosed
EP-0638112-A1 LIQUID CRYSTAL COMPOUNDS HAVING PERFLUOROETHER TERMINAL PORTIONS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1995-02-15 EP disclosed
US-5377033-A Ferroelectric liquid crystal device with an organosilesquioxane alignment layer and a polyamide or polyester alignment layer MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1994-12-27 US disclosed
US-5362919-A Direct fluorination process for making perfluorinated organic substances MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1994-11-08 US disclosed
EP-0609200-A1 DIRECT FLUORINATION PROCESS FOR MAKING PERFLUORINATED ORGANIC SUBSTANCES MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1994-08-10 EP disclosed
EP-0579545-A1 Liquid crystal display device MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1994-01-19 EP disclosed
US-5262082-A Ferroelectric liquid crystal compounds having perfluoroether terminal portions MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1993-11-16 US disclosed
WO-1993022396-A1 LIQUID CRYSTAL COMPOUNDS HAVING PERFLUOROETHER TERMINAL PORTIONS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1993-11-11 WO disclosed
WO-1990006296-A1 DIRECT FLUORINATION PROCESS FOR MAKING PERFLUORINATED ORGANIC SUBSTANCES MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1990-06-14 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120021253-A1 LUBRICANT COMPOSITION AND USE THEREOF MUC1, F12, SFN ALDH1A1 3731/4885F2 28/4885PRSS1 3007/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.