Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.45 |
| ▸ | CES1 | P23141 | 1/20 | 0.45 |
| ▸ | LARS1 | Q9P2J5 | 1/20 | 0.42 |
| ▸ | ANPEP | P15144 | 1/20 | 0.41 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.41 |
| ▸ | DNPEP | Q9ULA0 | 1/20 | 0.41 |
| ▸ | ELANE | P08246 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.40 |
| ▸ | CCR1 | P32246 | 2/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29491550 | 0.86 | SLC7A5 (0.52) | CES2CES1LARS1ANPEPRNPEP | |
| SCHEMBL4420284 | 0.84 | GRN (0.40) | LARS1ANPEPRNPEPDNPEPELANE | |
| SCHEMBL8507553 | 0.81 | CES2 (0.49) | CES2CES1MEN1GAAKMT2A | |
| SCHEMBL2460854 | 0.76 | TDP1 (0.50) | CES2CES1MEN1KMT2AATM | |
| SCHEMBL1969120 | 0.75 | L3MBTL1 (0.41) | CES2CES1GAAATMRECQL | |
| SCHEMBL11036149 | 0.75 | LMNA (0.46) | LARS1ANPEPRNPEPDNPEPELANE | |
| SCHEMBL5495906 | 0.75 | MDM2 (0.43) | CES2CES1MEN1KMT2AATM | |
| SCHEMBL11036148 | 0.75 | LMNA (0.46) | LARS1ANPEPRNPEPDNPEPELANE | |
| SCHEMBL27493547 | 0.74 | CES2 (0.61) | CES2CES1MEN1GAAKMT2A | |
| SCHEMBL3657476 | 0.74 | SLC7A5 (0.53) | CES2CES1MEN1GAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060281687-A1 | Cyclin groove inhibitors | CYCLACEL LIMITED (GB) | 2006-12-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060281687-A1 | Cyclin groove inhibitors | CCNC, CCNH, CCNI | CES2 3654/4885CES1 3829/4885LARS1 2522/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.