Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.45 |
| ▸ | SCN1A | P35498 | 1/20 | 0.43 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.43 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | LARS1 | Q9P2J5 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | ANPEP | P15144 | 1/20 | 0.39 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.39 |
| ▸ | DNPEP | Q9ULA0 | 1/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.39 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.39 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11036148 | 1.00 | LMNA (0.46) | LMNACYP1A2CYP3A4MAOASLC7A5 | |
| SCHEMBL29491550 | 0.83 | SLC7A5 (0.52) | LMNASLC7A5NPC1RAB9ALARS1 | |
| SCHEMBL8936829 | 0.81 | ALDH1A1 (0.44) | SLC7A5SLC6A3LARS1SLC6A2SLC6A4 | |
| SCHEMBL27707450 | 0.80 | SLC7A5 (0.44) | SLC7A5SLC6A3LARS1SLC6A2SLC6A4 | |
| SCHEMBL11619590 | 0.79 | SLC6A3 (0.41) | LMNACYP1A2CYP3A4MAOASCN1A | |
| SCHEMBL31407014 | 0.78 | TSHR (0.50) | LMNASLC6A3NPC1RAB9ASLC6A2 | |
| SCHEMBL9364482 | 0.78 | LMNA (0.44) | LMNACYP1A2CYP3A4MAOASCN1A | |
| SCHEMBL10797389 | 0.76 | MEN1 (0.47) | CYP3A4SLC7A5LARS1ANPEPRNPEP | |
| SCHEMBL2449415 | 0.76 | KDM4E (0.52) | LMNACYP1A2CYP3A4MAOASCN1A | |
| SCHEMBL6018034 | 0.75 | CES2 (0.45) | SLC7A5LARS1ANPEPRNPEPDNPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4537773-A | α-Aminoboronic acid derivatives | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1985-08-27 | — | — | US | disclosed |