Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK1 | Q13464 | 1/20 | 0.59 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.58 |
| ▸ | PIM1 | P11309 | 1/20 | 0.56 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.56 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 3/20 | 0.56 |
| ▸ | RAB9A | P51151 | 3/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.55 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.53 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.53 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.53 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.53 |
| ▸ | NAMPT | P43490 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | JAK2 | O60674 | 1/20 | 0.51 |
| ▸ | TYK2 | P29597 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4888537 | 0.84 | KDM4E (0.65) | ROCK1ROCK2PIM1PIM3PIM2 | |
| SCHEMBL2730773 | 0.84 | PIM1 (0.72) | PIM1PIM3PIM2HTTNPC1 | |
| SCHEMBL28304288 | 0.83 | RAB9A (0.62) | ROCK1ROCK2PIM1PIM3PIM2 | |
| SCHEMBL18843417 | 0.83 | NPC1 (0.57) | ROCK1NPC1RAB9APTPN1P4HTM | |
| SCHEMBL259311 | 0.81 | MEN1 (0.65) | HTTNPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL28350597 | 0.79 | MEN1 (0.60) | PIM1HTTNPC1RAB9AALDH1A1 | |
| SCHEMBL16671586 | 0.79 | ABL1 (0.51) | ROCK1ROCK2PIM1PIM3PIM2 | |
| SCHEMBL9720272 | 0.79 | ROCK2 (0.71) | ROCK1ROCK2PIM1PIM3PIM2 | |
| SCHEMBL20577434 | 0.78 | PIM1 (0.52) | ROCK1ROCK2PIM1PIM3PIM2 | |
| SCHEMBL17159814 | 0.78 | PIM1 (0.69) | ROCK1PIM1PIM3PIM2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025041008-A1 | SYNERGISTIC PESTICIDAL COMPOSITION | MALHOTRA SUNITA (IN) | 2025-02-27 | — | — | WO | claimed |
| US-9382197-B2 | Substituted hydroxamic acids and uses thereof | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2016-07-05 | — | — | US | claimed |
| US-8115012-B2 | Process for preparing difluoromethylpyrazolyl carboxylates | BASF SE (DE) | 2012-02-14 | — | — | US | claimed |
| US-20100069646-A1 | Process for preparing difluoromethylpyrazolyl carboxylates | BASF SE (DE) | 2010-03-18 | — | — | US | claimed |
| EP-2086944-B1 | PROCESS FOR PREPARING DIFLUOROMETHYLPYRAZOLYL CARBOXYLATES | BASF SE (DE) | 2010-01-13 | — | — | EP | claimed |
| CN-112888682-A | Heteroaryl aminoquinolines and analogs | 拜耳公司 | 2021-06-01 | — | — | CN | disclosed |
| CN-109970654-A | A series of substitution 2- phenylpyrazole derivatives and its preparation method and application | 郑州大学 | 2019-07-05 | — | — | CN | disclosed |
| EP-2496560-B1 | PROCESS FOR PREPARING 1,3-DISUBSTITUTED PYRAZOLE COMPOUNDS | BASF SE (DE) | 2015-04-22 | — | — | EP | disclosed |
| EP-2496561-B1 | PROCESS FOR PREPARING AMINALE AND THEIR USE FOR PREPARING 1,3-DISUBSTITUTED PYRAZOLE COMPOUNDS | BASF SE (DE) | 2014-06-04 | — | — | EP | disclosed |
| US-8362273-B2 | Process for preparing aminale and their use for preparing 1,3-disubstituted pyrazole compounds | BASF SE (DE) | 2013-01-29 | — | — | US | disclosed |
| US-8362272-B2 | Process for preparing 1,3-disubstituted pyrazole compounds | BASF SE (DE) | 2013-01-29 | — | — | US | disclosed |
| EP-2496560-A1 | PROCESS FOR PREPARING 1,3-DISUBSTITUTED PYRAZOLE COMPOUNDS | BASF SE (DE) | 2012-09-12 | — | — | EP | disclosed |
| WO-2011054732-A1 | PROCESS FOR PREPARING 1,3-DISUBSTITUTED PYRAZOLE COMPOUNDS | BASF SE (DE) | 2011-05-12 | — | — | WO | disclosed |
| WO-2011054733-A1 | PROCESS FOR PREPARING AMINALE AND THEIR USE FOR PREPARING 1,3-DISUBSTITUTED PYRAZOLE COMPOUNDS | BASF SE (DE) | 2011-05-12 | — | — | WO | disclosed |
| US-20100069646-A1 | Process for preparing difluoromethylpyrazolyl carboxylates | BASF SE (DE) | 2010-03-18 | — | — | US | disclosed |
| US-20090203523-A1 | Fungicidal Mixtures Made From 1-Methylpyrazol-4-Ylcarboxanilides | BASF AKTIENGESSELLSCHFT (DE) | 2009-08-13 | — | — | US | disclosed |
| US-20090123561-A1 | Fungicide mixtures based on 1-methyl-pyrazol-4-ylcarboxanilides | BASF AKTIENGESELLLSCHAFT (DE) | 2009-05-14 | — | — | US | disclosed |
| US-20070060566-A1 | Benzazepine derivatives as histamine h3 antagonists | GLAXO GROUP LIMITED (GB) | 2007-03-15 | — | — | US | disclosed |
| US-6414013-B1 | KINASE INHIBITORS; ANTICANCER AGENTS | PHARMACIA & UPJOHN S.P.A. (IT) | 2002-07-02 | — | — | US | disclosed |
| WO-1993011117-A1 | PYRAZOLE CARBOXANILIDE FUNGICIDES | MONSANTO COMPANY (US) | 1993-06-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100069646-A1 | Process for preparing difluoromethylpyrazolyl carboxylates | HCN2, HCN3, C9 | ROCK1 1722/4885ROCK2 1492/4885PIM1 900/4885 |
| US-20090203523-A1 | Fungicidal Mixtures Made From 1-Methylpyrazol-4-Ylcarboxanilides | CTRL, CYP4X1, SNU13 | ROCK1 3299/4885ROCK2 3809/4885PIM1 1283/4885 |
| US-20090123561-A1 | Fungicide mixtures based on 1-methyl-pyrazol-4-ylcarboxanilides | CBR3, CBR1, CTRL | ROCK1 3256/4885ROCK2 3832/4885PIM1 932/4885 |
| US-20070060566-A1 | Benzazepine derivatives as histamine h3 antagonists | HRH3, HRH4, HRH1 | ROCK1 4207/4885ROCK2 3702/4885PIM1 1689/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.