⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4346946 | 0.82 | TYMS (0.58) | — | |
| SCHEMBL1396820 | 0.79 | ENPEP (0.46) | — | |
| SCHEMBL242286 | 0.78 | ENPEP (0.50) | — | |
| SCHEMBL3420165 | 0.77 | — | — | |
| SCHEMBL5720460 | 0.75 | FDPS (0.57) | — | |
| SCHEMBL1231383 | 0.75 | THRB (0.46) | — | |
| SCHEMBL1230857 | 0.75 | THRB (0.46) | — | |
| SCHEMBL11660658 | 0.75 | ALDH1A1 (0.48) | — | |
| SCHEMBL6232069 | 0.75 | ENPEP (0.43) | — | |
| SCHEMBL701768 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 88 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994013688-A1 | DNA-ARMED RIBOZYMES AND MINIZYMES | GENE SHEARS PTY. LIMITED (AU) | 1994-06-23 | — | — | WO | claimed |
| EP-3980502-A1 | HEAT-SENSITIVE AQUEOUS POLYURETHANE DISPERSION AND METHOD FOR PREPARING THE SAME | Dow Global Technologies LLC (US) | 2022-04-13 | — | — | EP | disclosed |
| EP-3938417-A1 | WATERBORNE POLYURETHANE DISPERSION AND METHOD FOR PREPARING SAME | Dow Global Technologies LLC (US) | 2022-01-19 | — | — | EP | disclosed |
| EP-3938413-A1 | WATERBORNE POLYURETHANE DISPERSION AND METHOD FOR PREPARING SAME | Dow Global Technologies LLC (US) | 2022-01-19 | — | — | EP | disclosed |
| WO-2020243899-A1 | HEAT-SENSITIVE AQUEOUS POLYURETHANE DISPERSION AND METHOD FOR PREPARING THE SAME | DOW GLOBAL TECHNOLOGIES LLC (US) | 2020-12-10 | — | — | WO | disclosed |
| WO-2020187336-A1 | WATERBORNE POLYURETHANE DISPERSION AND METHOD FOR PREPARING SAME | DOW GLOBAL TECHNOLOGIES LLC (US) | 2020-09-24 | — | — | WO | disclosed |
| WO-2020186377-A1 | WATERBORNE POLYURETHANE DISPERSION AND METHOD FOR PREPARING SAME | DOW GLOBAL TECHNOLOGIES LLC (US) | 2020-09-24 | — | — | WO | disclosed |
| WO-2020097839-A1 | SYNTHETIC LEATHER ARTICLE AND METHOD FOR PREPARING THE SAME | DOW GLOBAL TECHNOLOGIES LLC (US) | 2020-05-22 | — | — | WO | disclosed |
| WO-2020097838-A1 | SYNTHETIC LEATHER ARTICLE AND METHOD FOR PREPARING SAME | DOW GLOBAL TECHNOLOGIES LLC (US) | 2020-05-22 | — | — | WO | disclosed |
| US-9868955-B2 | Human toll-like receptor inhibitors and methods of use thereof | DYNAVAX TECHNOLOGIES CORPORATION (US) | 2018-01-16 | — | — | US | disclosed |
| US-6555668-B2 | Comprising a non-nucleotide in a single-stranded region; hammerhead ribozyme having a non-nucleotide in the catalytic core; synthesis of abasic ribonucleoside mimetics | RIBOZYME PHARMACEUTICALS, INC. | 2003-04-29 | — | — | US | disclosed |
| WO-2003000922-A2 | CHIMERIC IMMUNOMODULATORY COMPOUNDS AND METHODS OF USING THE SAME | DYNAVAX TECHNOLOGIES CORPORATION (US) | 2003-01-03 | — | — | WO | disclosed |
| US-20020193579-A1 | Non-nucleotide containing enzymatic nucleic acid | RIBOZYME PHARMACEUTICALS, INC. | 2002-12-19 | — | — | US | disclosed |
| US-6362323-B1 | HAVING ACTIVITY TO CLEAVE AN RNA OR DNA MOLECULE | RIBOZYME PHARMACEUTICALS, INC. | 2002-03-26 | — | — | US | disclosed |
| US-6117657-A | ENZYMATIC NUCLEIC ACID MOLECULE CONTAINING ONE OR MORE NON-NUCLEOTIDE MIMETICS, AND HAVING ACTIVITY TO CLEAVE AN RNA OR DNA MOLECULE | RIBOZYME PHARMACEUTICALS, INC. (US) | 2000-09-12 | — | — | US | disclosed |
| EP-0908464-A1 | Process for the preparation of hydroxyphosphonates and their use as flame retardants in polymers | BASF AKTIENGESELLSCHAFT (DE) | 1999-04-14 | — | — | EP | disclosed |
| US-5891683-A | Non-nucleotide containing enzymatic nucleic acid | RIBOZYME PHARMACEUTICALS, INC. (US) | 1999-04-06 | — | — | US | disclosed |
| EP-0799313-A2 | METHOD AND REAGENT FOR TREATMENT OF ARTHRITIC CONDITIONS, INDUCTION OF GRAFT TOLERANCE AND REVERSAL OF IMMUNE RESPONSES | RIBOZYME PHARMACEUTICALS, INC. (US) | 1997-10-08 | — | — | EP | disclosed |
| WO-1996018736-A2 | METHOD AND REAGENT FOR TREATMENT OF ARTHRITIC CONDITIONS, INDUCTION OF GRAFT TOLERANCE AND REVERSAL OF IMMUNE RESPONSES | RIBOZYME PHARMACEUTICALS, INC. (US) | 1996-06-20 | — | — | WO | disclosed |
| WO-1994013688-A1 | DNA-ARMED RIBOZYMES AND MINIZYMES | GENE SHEARS PTY. LIMITED (AU) | 1994-06-23 | — | — | WO | disclosed |