Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 1/20 | 0.42 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CTSV | O60911 | 1/20 | 0.40 |
| ▸ | CTSL | P07711 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5591572 | 0.87 | CYP19A1 (0.41) | ABCB1ABCC1PKMRAB9AMAPK1 | |
| SCHEMBL3359456 | 0.83 | MAPK1 (0.51) | PKMRAB9AMAPK1NPC1L3MBTL1 | |
| SCHEMBL594650 | 0.79 | MAPT (0.61) | ABCB1MAPK1L3MBTL1POLBKMT2A | |
| SCHEMBL709343 | 0.77 | KMT2A (0.65) | PKMRAB9AMAPK1NPC1POLB | |
| SCHEMBL1312167 | 0.76 | POLB (0.57) | ABCB1RAB9ANPC1POLBKMT2A | |
| SCHEMBL31473699 | 0.76 | POLB (0.57) | ABCB1RAB9ANPC1POLBKMT2A | |
| SCHEMBL22897914 | 0.75 | TSHR (0.43) | RAB9ANPC1POLBKMT2AMEN1 | |
| SCHEMBL4633259 | 0.74 | CTSV (0.43) | ABCB1ABCC1KDM4EKMT2AMEN1 | |
| SCHEMBL29197789 | 0.74 | PIN1 (0.46) | PKMRAB9ANPC1L3MBTL1KMT2A | |
| SCHEMBL337857 | 0.74 | L3MBTL1 (0.68) | PKMMAPK1L3MBTL1POLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1613626-A1 | CYCLIC BENZIMIDAZOLES | ALTANA Pharma AG (DE) | 2006-01-11 | — | — | EP | disclosed |
| WO-2004087701-A1 | CYCLIC BENZIMIDAZOLES | ALTANA PHARMA AG (DE) | 2004-10-14 | — | — | WO | disclosed |