SCHEMBL6020097

SCHEMBL6020097

CCN(C#N)C(=O)C(Cc1ccccc1)NC(=O)Nc1ccc(C(F)(F)F)cc1

nearest known ligand 0.66

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
FPR2 P25090 10/20 0.66
MTOR P42345 1/20 0.46
TP53 P04637 1/20 0.45
POLB P06746 1/20 0.45
MAPT P10636 1/20 0.45
TACR2 P21452 2/20 0.45
CTSL P07711 3/20 0.44
CTSK P43235 3/20 0.44
IDO1 P14902 1/20 0.44
CTSB P07858 2/20 0.44
CTSS P25774 2/20 0.44
CA12 O43570 1/20 0.43
CA1 P00915 1/20 0.43
CA2 P00918 1/20 0.43
CA9 Q16790 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6442131 0.93 FPR2 (0.57) FPR2MTORTP53POLBMAPT
SCHEMBL6020374 0.91 FPR2 (0.53) FPR2MTORCTSLCTSKCTSB
SCHEMBL6020534 0.90 FPR2 (0.53) FPR2CTSLCTSKCTSBCTSS
SCHEMBL6020184 0.89 FPR2 (0.51) FPR2CTSLCTSKCTSBCTSS
SCHEMBL6019649 0.87 FPR2 (0.49) FPR2MAPTCTSLCTSKCTSB
SCHEMBL6020699 0.87 FPR2 (0.68) FPR2MAPTCTSLCTSKCTSB
SCHEMBL6020284 0.87 FPR2 (0.51) FPR2
SCHEMBL6019541 0.85 FPR2 (0.47) FPR2MTORMAPTCTSLCTSK
SCHEMBL6020507 0.85 FPR2 (0.55) FPR2TACR2
SCHEMBL6020927 0.83 FPR2 (0.52) FPR2TP53CA12CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20060252813-A1 Apparatus for curing a composite laminate JERINI AG (DE) 2006-11-09 US claimed
EP-1433778-A1 Use of nitriles as rotamase inhibitors Jerini AG (DE) 2004-06-30 EP claimed
EP-1433779-A1 Use of nitriles as inhibitors of non-proteolytic enzymes Jerini AG (DE) 2004-06-30 EP claimed
US-20060252813-A1 Apparatus for curing a composite laminate JERINI AG (DE) 2006-11-09 US disclosed
EP-1433778-A1 Use of nitriles as rotamase inhibitors Jerini AG (DE) 2004-06-30 EP disclosed
EP-1433779-A1 Use of nitriles as inhibitors of non-proteolytic enzymes Jerini AG (DE) 2004-06-30 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060252813-A1 Apparatus for curing a composite laminate DHX29, HDHD5, DHRS9 FPR2 3247/4885MTOR 4497/4885TP53 4859/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.