Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 3/20 | 0.31 |
| ▸ | APP | P05067 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22589820 | 0.83 | IDO1 (0.48) | IDO1APPMEN1KMT2ACA2 | |
| SCHEMBL6020749 | 0.83 | CA2 (0.32) | CA2CA9 | |
| SCHEMBL4076437 | 0.81 | APP (0.46) | IDO1APPCA2CA9CYP3A4 | |
| SCHEMBL3365610 | 0.81 | PRSS1 (0.39) | IDO1APPMEN1KMT2ACA2 | |
| SCHEMBL17061043 | 0.81 | CYP3A4 (0.50) | IDO1APPCYP3A4 | |
| SCHEMBL4066062 | 0.79 | CES2 (0.38) | IDO1APPMEN1KMT2ACA2 | |
| SCHEMBL5432095 | 0.79 | AGXT (0.48) | IDO1CA2CA9 | |
| SCHEMBL4938371 | 0.79 | IDO1 (0.48) | IDO1APPMEN1KMT2ACA2 | |
| SCHEMBL4055238 | 0.79 | IDO1 (0.48) | IDO1APPCA2CA9 | |
| SCHEMBL28119658 | 0.79 | ABAT (0.48) | CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1620110-A2 | IMMUNOMODULATOR PHOSPHONATE CONJUGATES | GILEAD SCIENCES, INC. (US) | 2006-02-01 | — | — | EP | disclosed |
| WO-2004096236-A2 | IMMUNOMODULATOR PHOSPHONATE CONJUGATES | GILEAD SCIENCES, INC. (US) | 2004-11-11 | — | — | WO | disclosed |