Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPOR | P19235 | 3/20 | 0.49 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.48 |
| ▸ | CASP1 | P29466 | 3/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | CTSS | P25774 | 2/20 | 0.46 |
| ▸ | CTSK | P43235 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | CTSL | P07711 | 1/20 | 0.45 |
| ▸ | CTSB | P07858 | 1/20 | 0.45 |
| ▸ | ITGB3 | P05106 | 5/20 | 0.45 |
| ▸ | ITGA2B | P08514 | 5/20 | 0.45 |
| ▸ | MMP9 | P14780 | 1/20 | 0.44 |
| ▸ | MMP8 | P22894 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3929268 | 0.86 | ITGB3 (0.48) | EPORPTPN1CTSSCTSKALDH1A1 | |
| SCHEMBL6021993 | 0.84 | CTSL (0.61) | CASP1CTSSCTSKCTSLCTSB | |
| SCHEMBL27677478 | 0.81 | PPARG (0.62) | CASP1ITGB3ITGA2B | |
| SCHEMBL3917891 | 0.81 | PPARG (0.62) | CASP1ITGB3ITGA2B | |
| SCHEMBL3930097 | 0.79 | EPOR (0.57) | EPOR | |
| SCHEMBL6441561 | 0.76 | ITGB3 (0.51) | CASP1ALDH1A1ITGB3ITGA2B | |
| SCHEMBL7360694 | 0.75 | CTSS (0.63) | HDAC8CTSSCTSKCTSLCTSB | |
| SCHEMBL3929273 | 0.74 | ITGB3 (0.47) | CASP1ALDH1A1ITGB3ITGA2B | |
| SCHEMBL29938811 | 0.74 | CTSS (0.55) | PTPN1CTSSCTSKALDH1A1CTSL | |
| SCHEMBL29938529 | 0.74 | CTSS (0.55) | PTPN1CTSSCTSKALDH1A1CTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1725577-A1 | ANTITHROMBOTIC COMPOUND | Sanofi-Aventis (FR) | 2006-11-29 | — | — | EP | disclosed |
| WO-2005090382-A1 | ANTITHROMBOTIC COMPOUND | SANOFI-AVENTIS (FR) | 2005-09-29 | — | — | WO | disclosed |
| EP-1574516-A1 | Antithrombotic compound | Sanofi-Aventis (FR) | 2005-09-14 | — | — | EP | disclosed |