Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Propene. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Propene SCHEMBL28384458 | 0.95 | — | — | |
| Propene SCHEMBL1583881 | 0.95 | — | — | |
| Propene SCHEMBL118002 | 0.91 | — | — | |
| Propene SCHEMBL16568392 | 0.87 | — | — | |
| Propene SCHEMBL19915254 | 0.87 | — | — | |
| Propene SCHEMBL16338827 | 0.84 | — | — | |
| Propene SCHEMBL16176242 | 0.75 | — | — | |
| Propene SCHEMBL3432457 | 0.75 | — | — | |
| Propene SCHEMBL28449839 | 0.75 | — | — | |
| Propene SCHEMBL342422 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160122342-A1 | ENHANCER OF ZESTE HOMOLOG 2 INHIBITORS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY (NO.2) LIMITED (GB) | 2016-05-05 | — | — | US | disclosed |
| EP-3004096-A1 | ENHANCER OF ZESTE HOMOLOG 2 INHIBITORS | Glaxosmithkline Intellectual Property (No. 2) Limited (GB) | 2016-04-13 | — | — | EP | disclosed |
| WO-2014195919-A1 | ENHANCER OF ZESTE HOMOLOG 2 INHIBITORS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY (NO.2) LIMITED (GB) | 2014-12-11 | — | — | WO | disclosed |
| EP-1613646-A2 | PROCESS FOR PREPARATION OF CYCLOSPORIN \"A\" ANALOGUES HAVING A TERMINAL DIENE GROUP | Isotechnika Inc. (CA) | 2006-01-11 | — | — | EP | disclosed |
| US-20040220091-A1 | Process for preparation of cyclosporin A analogs | ISOTECHNIKA INC. (CA) | 2004-11-04 | — | — | US | disclosed |
| WO-2004089960-A2 | PROCESS FOR PREPARATION OF CYCLOSPORIN “A” ANALOGUES HAVING A TERMINAL DIENE GROUP | ISOTECHNIKA INC. (CA) | 2004-10-21 | — | — | WO | disclosed |