Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.56 |
| ▸ | BRD4 | O60885 | 1/20 | 0.55 |
| ▸ | PKM | P14618 | 2/20 | 0.52 |
| ▸ | AR | P10275 | 12/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | ALPG | P10696 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | BRAF | P15056 | 1/20 | 0.42 |
| ▸ | CCR9 | P51686 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5860071 | 0.90 | SLC22A12 (0.50) | SLC22A12BRD4PKMARGAA | |
| SCHEMBL6022363 | 0.86 | FFAR1 (0.55) | PKMARGAAPOLBTP53 | |
| SCHEMBL6023623 | 0.86 | PKM (0.70) | PKMARGAAPOLBMAPT | |
| SCHEMBL6023208 | 0.85 | PKM (0.60) | PKMARGAAPOLBLMNA | |
| SCHEMBL6022442 | 0.82 | PKM (0.54) | PKMARGAALMNATP53 | |
| SCHEMBL6022292 | 0.82 | SLC22A12 (0.55) | SLC22A12PKMARGAAPOLB | |
| SCHEMBL6023010 | 0.82 | L3MBTL1 (0.54) | PKMARGAAPOLBLMNA | |
| SCHEMBL6022246 | 0.82 | TP53 (0.58) | BRD4PKMGAAPOLBLMNA | |
| SCHEMBL6022358 | 0.82 | PKM (0.51) | PKMARGAAPOLB | |
| SCHEMBL6022578 | 0.81 | AR (0.52) | PKMARGAAPOLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7009052-B2 | Sulfonamide derivatives | WARNER LAMBERT COMPANY LLC (US) | 2006-03-07 | — | — | US | disclosed |