Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 3/20 | 0.52 |
| ▸ | AR | P10275 | 11/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 7/20 | 0.44 |
| ▸ | TP53 | P04637 | 5/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5861484 | 0.90 | AR (0.45) | PKMARGAAMAPTMEN1 | |
| SCHEMBL6023208 | 0.85 | PKM (0.60) | PKMARGAAPOLBMAPT | |
| SCHEMBL6022537 | 0.83 | PKM (0.51) | PKMARGAAPOLBMAPT | |
| SCHEMBL6022363 | 0.83 | FFAR1 (0.55) | PKMARGAAPOLBMAPT | |
| SCHEMBL6023623 | 0.83 | PKM (0.70) | PKMARGAAPOLBMAPT | |
| SCHEMBL6023096 | 0.83 | MAPT (0.62) | PKMARGAAPOLBMAPT | |
| SCHEMBL6022246 | 0.82 | TP53 (0.58) | PKMGAAPOLBMAPTTP53 | |
| SCHEMBL6022358 | 0.82 | PKM (0.51) | PKMARGAAPOLBALDH1A1 | |
| SCHEMBL6022442 | 0.82 | PKM (0.54) | PKMARGAATP53KMT2A | |
| SCHEMBL6023010 | 0.82 | L3MBTL1 (0.54) | PKMARGAAPOLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7009052-B2 | Sulfonamide derivatives | WARNER LAMBERT COMPANY LLC (US) | 2006-03-07 | — | — | US | disclosed |