Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | MAPT | P10636 | 3/20 | 0.58 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.55 |
| ▸ | KDR | P35968 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | THRB | P10828 | 1/20 | 0.53 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.51 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.51 |
| ▸ | CDYL2 | Q8N8U2 | 4/20 | 0.50 |
| ▸ | CDYL | Q9Y232 | 4/20 | 0.50 |
| ▸ | CDY1; CDY1B | Q9Y6F8 | 4/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | CES2 | O00748 | 1/20 | 0.50 |
| ▸ | CES1 | P23141 | 1/20 | 0.50 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.50 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4873274 | 0.83 | ALDH1A1 (0.71) | MEN1KMT2AALDH1A1MAPTKDR | |
| Hydrochloric Acid SCHEMBL3844533 | 0.82 | ALDH1A1 (0.69) | MEN1KMT2AALDH1A1MAPTKDR | |
| SCHEMBL11395399 | 0.80 | KDM5C (0.51) | MEN1KMT2AALDH1A1MAPTKDM4E | |
| SCHEMBL11106554 | 0.80 | ALDH1A1 (0.62) | MEN1KMT2AALDH1A1MAPTKDM4E | |
| SCHEMBL3846426 | 0.79 | L3MBTL1 (0.70) | MEN1KMT2AALDH1A1HPGD | |
| SCHEMBL10775964 | 0.78 | SMN1; SMN2 (0.72) | MEN1KMT2AALDH1A1MAPTKDR | |
| SCHEMBL31419990 | 0.78 | DRD4 (0.66) | MEN1KMT2AALDH1A1MAPTKDR | |
| SCHEMBL1189519 | 0.78 | ALDH1A1 (0.63) | MEN1KMT2AALDH1A1MAPTKDR | |
| Hydrochloric Acid SCHEMBL31419981 | 0.77 | DRD4 (0.65) | MEN1KMT2AALDH1A1MAPTKDR | |
| SCHEMBL11104586 | 0.77 | KDR (0.61) | MEN1KMT2AALDH1A1MAPTKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7078407-B2 | 4-hydroxycinnamamide derivatives as antioxidants and pharmaceutical compositions containing them | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2006-07-18 | — | — | US | disclosed |
| US-20030162789-A1 | 4-Hydroxycinnamamide derivatives as antioxidants and pharmaceutical compositions containing them | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2003-08-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030162789-A1 | 4-Hydroxycinnamamide derivatives as antioxidants and pharmaceutical compositions containing them | HTT, PARK7, NQO1 | MEN1 3297/4885KMT2A 1377/4885ALDH1A1 804/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.