SCHEMBL602307

SCHEMBL602307

Nc1cccc(C(=O)O)c1F

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MMP2 P08253 1/20 0.61
ALB P02768 1/20 0.50
G6PD P11413 1/20 0.50
CASP7 P55210 1/20 0.50
CASP6 P55212 1/20 0.50
KEAP1 Q14145 1/20 0.48
ALDH1A1 P00352 2/20 0.48
ALOX15 P16050 1/20 0.48
CDC25B P30305 1/20 0.46
MAPT P10636 2/20 0.45
GAA P10253 1/20 0.45
NAPRT Q6XQN6 3/20 0.44
IDO1 P14902 1/20 0.44
KDM4E B2RXH2 4/20 0.44
NPC1 O15118 1/20 0.44
CASP3 P42574 1/20 0.44
RAB9A P51151 1/20 0.44
SENP8 Q96LD8 1/20 0.44
HSD17B10 Q99714 1/20 0.44
SENP7 Q9BQF6 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31227767 1.00 MMP2 (0.61) MMP2ALBG6PDCASP7CASP6
Hydrochloric Acid SCHEMBL28822564 0.98 MMP2 (0.59) MMP2ALBG6PDCASP7CASP6
Trifluoroacetic Acid SCHEMBL3783854 0.91 MMP2 (0.52) MMP2ALBG6PDCASP7CASP6
Deanol SCHEMBL8783637 0.85 MMP2 (0.46) MMP2ALBG6PDCASP7CASP6
SCHEMBL336107 0.84 ALDH1A1 (0.60) MMP2ALBG6PDCASP7CASP6
SCHEMBL31413038 0.83 MMP2 (0.45) MMP2ALBG6PDCASP7CASP6
SCHEMBL27651120 0.83 MMP2 (0.45) MMP2CASP7KEAP1ALDH1A1ALOX15
SCHEMBL30623038 0.83 MMP2 (0.45) MMP2CASP7KEAP1ALDH1A1ALOX15
SCHEMBL21707970 0.81 ALDH1A1 (0.52) MMP2ALBG6PDCASP7CASP6
SCHEMBL13862137 0.81 MMP2 (0.44) MMP2ALDH1A1MAPTGAAKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 181 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119490423-A Method for preparing 2-fluoro-3-aminobenzoic acid and ester compound thereof 沈阳中化农药化工研发有限公司 2025-02-21 CN claimed
CN-119490422-A Synthesis method of 2-fluoro-3-aminobenzoic acid and ester compound thereof 沈阳中化农药化工研发有限公司 2025-02-21 CN claimed
CN-119490421-A Method for synthesizing 2-fluoro-3-aminobenzoic acid and ester compound thereof 沈阳中化农药化工研发有限公司 2025-02-21 CN claimed
CN-119490424-A Preparation method of 2-fluoro-3-aminobenzoic acid and ester compound 沈阳中化农药化工研发有限公司 2025-02-21 CN claimed
WO-2025036387-A1 PREPARATION METHOD FOR 2-FLUORO-3-AMINOBENZOIC ACID AND ESTER COMPOUNDS 沈阳中化农药化工研发有限公司 2025-02-20 WO claimed
WO-2025036384-A1 METHOD FOR PREPARING 2-CHLORO-3-AMINOBENZOIC ACID AND ESTER COMPOUND THEREOF 沈阳中化农药化工研发有限公司 2025-02-20 WO claimed
CN-114920661-B Synthesis method of 2-fluoro-3-aminobenzoic acid 浙江沙星科技股份有限公司 2024-01-02 CN claimed
CN-115850103-B Preparation method of 3-amino-2-fluorobenzoic acid methyl ester 北京颖泰嘉和生物科技股份有限公司 2023-04-28 CN claimed
CN-115850103-A Preparation method of 3-amino-2-fluorobenzoic acid methyl ester 北京颖泰嘉和生物科技股份有限公司 2023-03-28 CN claimed
CN-114920661-A Synthetic method of 2-fluoro-3-aminobenzoic acid 浙江沙星科技有限公司 2022-08-19 CN claimed
CN-121574054-B Preparation method of 2-fluoro-3-nitrobenzoic acid 济南国鼎医药科技有限公司 2026-05-15 CN disclosed
CN-121574054-A Preparation method of 2-fluoro-3-nitrobenzoic acid 济南国鼎医药科技有限公司 2026-02-27 CN disclosed
US-12427146-B2 C-terminal SRC kinase inhibitors InventisBio Co., Ltd. (CN) 2025-09-30 US disclosed
US-12280023-B2 Fluorophenyl beta-hydroxyethylamines and their use in the treatment of hyperglycaemia ATROGI AB (SE) 2025-04-22 US disclosed
CN-119552089-A Preparation method of 3-amino-2-fluorobenzoyl chloride and derivatives thereof 帕潘纳(北京)科技有限公司 2025-03-04 CN disclosed
US-20070082912-A1 Pyrrole compounds for the treatment of prostaglandine mediated diseases GLAXO GROUP LIMITED (GB) 2007-04-12 US disclosed
EP-0831845-B1 DIPHOSPHONATE DERIVATIVES OF THERAPEUTIC AGENTS ELIZANOR BIOPHARMACEUTICALS IN (US) 2004-09-08 EP disclosed
EP-0831845-A4 DIPHOSPHONATE DERIVATIVES OF THERAPEUTIC AGENTS ELIZANOR BIOPHARMACEUTICALS IN (US) 1998-12-02 EP disclosed
EP-0831845-A1 DIPHOSPHONATE DERIVATIVES OF THERAPEUTIC AGENTS Elizanor Biopharmaceuticals, Inc. (US) 1998-04-01 EP disclosed
WO-1996040156-A1 DIPHOSPHONATE DERIVATIVES OF THERAPEUTIC AGENTS ELIZANOR BIOPHARMACEUTICALS, INC. (US) 1996-12-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12427146-B2 C-terminal SRC kinase inhibitors CSK, SRC, CSNK1G2 MMP2 2666/4885ALB 4762/4885G6PD 3330/4885
US-20070082912-A1 Pyrrole compounds for the treatment of prostaglandine mediated diseases PTGER1, PTGDR, PTGIR MMP2 3999/4885ALB 4172/4885G6PD 2022/4885
US-12280023-B2 Fluorophenyl beta-hydroxyethylamines and their use in the treatment of hyperglycaemia GPR119, SLC5A2, SLC5A1 MMP2 2417/4885ALB 500/4885G6PD 26/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.