SCHEMBL6023192

SCHEMBL6023192

[CH2]c1c(C(F)(F)F)ccc(C)c1C(F)(F)F

nearest known ligand 0.35

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
AR P10275 4/20 0.35
NOTUM Q6P988 1/20 0.32
S1PR1 P21453 2/20 0.31
HSD11B1 P28845 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5253646 0.81 AR (0.35) ARHSD11B1
SCHEMBL13199206 0.77 AR (0.41) ARHSD11B1
SCHEMBL12154091 0.75 CYP1A2 (0.33) ARNOTUMHSD11B1
SCHEMBL8049775 0.74 NOTUM (0.32) ARNOTUMHSD11B1
SCHEMBL25374949 0.71 GABRA1 (0.39) ARHSD11B1
SCHEMBL13160060 0.69 AR (0.33) ARHSD11B1
SCHEMBL13816869 0.69 TRPA1 (0.35) AR
SCHEMBL14423252 0.69 CYP1A2 (0.35)
SCHEMBL6629394 0.68 HSD11B1 (0.47) ARHSD11B1
SCHEMBL10800866 0.67 AR (0.33) ARNOTUMS1PR1HSD11B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7101900-B2 Benzyl amidoxime derivatives, intermediate products and method for their production and use as fungicides BASF AKTIENGESELLSCHAFT (DE) 2006-09-05 US disclosed
US-20050187265-A1 Novel benzyl amidoxime derivatives, intermediate products and method for their production and use as fungicides RHEINHEIMER JOACHIM (DE) 2005-08-25 US disclosed
US-6881742-B1 Benzyl amidoxime derivatives, intermediate products and method for their production and use as fungicides BASF AKTIENGESELLSCHAFT (DE) 2005-04-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050187265-A1 Novel benzyl amidoxime derivatives, intermediate products and method for their production and use as fungicides CBR3, CBR1, CYP1B1 AR 3155/4885NOTUM 651/4885S1PR1 3819/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.