Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.32 |
| ▸ | AR | P10275 | 2/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
| ▸ | CES2 | O00748 | 1/20 | 0.31 |
| ▸ | DAO | P14920 | 1/20 | 0.30 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7298662 | 0.81 | CES2 (0.34) | HSD11B1CES2DAO | |
| SCHEMBL13199206 | 0.77 | AR (0.41) | ARHSD11B1DAOTAS2R14 | |
| SCHEMBL12154091 | 0.75 | CYP1A2 (0.33) | NOTUMARHSD11B1 | |
| SCHEMBL6023192 | 0.74 | AR (0.35) | NOTUMARHSD11B1 | |
| SCHEMBL8066356 | 0.74 | GAA (0.34) | CES2 | |
| SCHEMBL14423252 | 0.74 | CYP1A2 (0.35) | — | |
| SCHEMBL10744876 | 0.71 | TDP2 (0.32) | — | |
| SCHEMBL394894 | 0.71 | GABRA1 (0.34) | — | |
| SCHEMBL12260037 | 0.69 | AR (0.33) | ARHSD11B1 | |
| SCHEMBL13160060 | 0.69 | AR (0.33) | ARHSD11B1TAS2R14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6057336-A | ANTIINFLAMMATORY AGENTS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2000-05-02 | — | — | US | disclosed |