Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 2/20 | 0.46 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.44 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3826924 | 0.81 | NPC1 (0.45) | AKR1C3GLATDP1RECQLALDH1A1 | |
| SCHEMBL6670487 | 0.80 | ALDH1A1 (0.48) | HSD17B10ALDH1A1KMT2A | |
| Hydrochloric Acid SCHEMBL27730029 | 0.79 | NPC1 (0.44) | AKR1C3GLATDP1RECQLALDH1A1 | |
| SCHEMBL1506725 | 0.78 | NPC1 (0.63) | AKR1C3GLATDP1RECQLMTNR1A | |
| SCHEMBL94681 | 0.78 | ALDH1A1 (0.51) | AKR1C3GLATDP1ALDH1A1TSHR | |
| SCHEMBL6208267 | 0.78 | ALDH1A1 (0.47) | AKR1C3GLATDP1RECQLALDH1A1 | |
| SCHEMBL6025421 | 0.78 | NPC1 (0.63) | AKR1C3GLATDP1RECQLMTNR1A | |
| SCHEMBL5892379 | 0.77 | HTT (0.43) | AKR1C3GLATDP1HSD17B10RECQL | |
| SCHEMBL5754950 | 0.77 | ALDH1A1 (0.39) | AKR1C3GLATDP1RECQLMTNR1A | |
| SCHEMBL2264042 | 0.77 | KMT2A (0.48) | TDP1RECQLMTNR1AMTNR1BALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1515 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11939404-B2 | Method for producing cyclized peptide having intramolecular S-S bond | AJINOMOTO CO., INC. (JP) | 2024-03-26 | — | — | US | claimed |
| CN-114716386-A | Novel exosome inhibitor and preparation method thereof | 北京和理咨询有限公司 | 2022-07-08 | — | — | CN | claimed |
| EP-3882255-A1 | METHOD FOR PRODUCING CYCLIZED PEPTIDE HAVING INTRAMOLECULAR S-S BOND | AJINOMOTO CO., INC. (JP) | 2021-09-22 | — | — | EP | claimed |
| US-20210277063-A1 | METHOD FOR PRODUCING CYCLIZED PEPTIDE HAVING INTRAMOLECULAR S-S BOND | AJINOMOTO CO., INC. (JP) | 2021-09-09 | — | — | US | claimed |
| CN-113039193-A | Method for producing cyclized peptide having intramolecular S-S bond | 味之素株式会社 | 2021-06-25 | — | — | CN | claimed |
| EP-3110828-B1 | CONTINUOUS FLOW PEPTIDE SYNTHESIS | UNIV SZEGEDI (HU) | 2020-12-09 | — | — | EP | claimed |
| US-10577459-B2 | Aliphatic poly(ester)s with thiol pendant groups | WISTRAND, Anna (SE) | 2020-03-03 | — | — | US | claimed |
| US-20180305495-A1 | ALIPHATIC POLY(ESTER)S WITH THIOL PENDANT GROUPS | PAPPALARDO, Daniela (IT) | 2018-10-25 | — | — | US | claimed |
| EP-3362500-A1 | ALIPHATIC POLY(ESTER)S WITH THIOL PENDANT GROUPS | Novus Scientific AB (SE) | 2018-08-22 | — | — | EP | claimed |
| EP-2800756-B1 | PEPTIDE C ALPHA-AMIDES, METHODS FOR PREPARING SAME AND USES THEREOF AS PRECURSORS OF PEPTIDE C ALPHA-THIOESTERS FOR PROTEIN SYNTHESIS | CENTRE NAT RECH SCIENT (FR) | 2018-04-25 | — | — | EP | claimed |
| WO-1994022840-A1 | SUBSTITUTED CAPROLACTAMS AND DERIVATIVES THEREOF USEFUL FOR TREATMENT OF HIV DISEASE | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1994-10-13 | — | — | WO | claimed |
| EP-0408371-B1 | Hemoregulatory peptides | SMITHKLINE BEECHAM CORP (US) | 1994-09-28 | — | — | EP | claimed |
| WO-1994019329-A1 | SUBSTITUTED CYCLIC CARBONYLS AND DERIVATIVES THEREOF USEFUL AS RETROVIRAL PROTEASE INHIBITORS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1994-09-01 | — | — | WO | claimed |
| WO-1993013789-A1 | HEMOREGULATORY PEPTIDES | SMITHKLINE BEECHAM CORPORATION (US) | 1993-07-22 | — | — | WO | claimed |
| WO-1993010807-A1 | HEMOREGULATORY PEPTIDES | SMITHKLINE BEECHAM CORPORATION (US) | 1993-06-10 | — | — | WO | claimed |
| CN-1054773-A | HEMOREGULATORY PEPTIDES | SMITHKLINE BEECHAM CORP (US) | 1991-09-25 | — | — | CN | claimed |
| EP-0408371-A1 | Hemoregulatory peptides | SMITHKLINE BEECHAM CORPORATION (US) | 1991-01-16 | — | — | EP | claimed |
| EP-0112135-B1 | BROMINATION OF CEPHALOSPORINS | ELI LILLY AND COMPANY (US) | 1988-01-13 | — | — | EP | claimed |
| US-4468514-A | Preparation of 3-bromocephalosporins from thiazoline azetidinones | ELI LILLY AND COMPANY (US) | 1984-08-28 | — | — | US | claimed |
| EP-0112135-A2 | Bromination of cephalosporins | ELI LILLY AND COMPANY (US) | 1984-06-27 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11939404-B2 | Method for producing cyclized peptide having intramolecular S-S bond | SPPL2B, PTMS, VIP | AKR1C3 3576/4885GLA 2680/4885TDP1 3529/4885 |
| US-10577459-B2 | Aliphatic poly(ester)s with thiol pendant groups | PARG, TST, CBS | AKR1C3 492/4885GLA 2716/4885TDP1 2088/4885 |
| US-20210277063-A1 | METHOD FOR PRODUCING CYCLIZED PEPTIDE HAVING INTRAMOLECULAR S-S BOND | SPPL2B, PTMS, VIP | AKR1C3 3576/4885GLA 2680/4885TDP1 3529/4885 |
| US-20180305495-A1 | ALIPHATIC POLY(ESTER)S WITH THIOL PENDANT GROUPS | PARG, TST, CBS | AKR1C3 492/4885GLA 2716/4885TDP1 2088/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.