Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.48 |
| ▸ | CYP2A6 | P11509 | 4/20 | 0.44 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.44 |
| ▸ | ABAT | P80404 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | TYR | P14679 | 1/20 | 0.40 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | ALDH1A3 | P47895 | 2/20 | 0.38 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 2/20 | 0.36 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.36 |
| ▸ | PARP3 | Q9Y6F1 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL60234 | 0.80 | AKR1C3 (0.48) | ALDH1A1HSD17B10KMT2A | |
| SCHEMBL743446 | 0.78 | HDAC8 (0.45) | KDM4EKMT2A | |
| SCHEMBL9199658 | 0.76 | CES2 (0.39) | ALDH1A1KDM4EKMT2A | |
| SCHEMBL295483 | 0.75 | CYP4A11 (0.50) | KDM4E | |
| SCHEMBL201938 | 0.74 | ALDH1A1 (0.64) | ALDH1A1KDM4EHSD17B10KMT2A | |
| Ammonia Solution, Strong SCHEMBL7802754 | 0.72 | ALDH1A1 (0.62) | ALDH1A1KDM4EHSD17B10KMT2A | |
| SCHEMBL5556185 | 0.72 | ALDH1A1 (0.46) | ALDH1A1KDM4ETYRHSD17B10KMT2A | |
| SCHEMBL7538748 | 0.71 | ALDH1A1 (0.55) | ALDH1A1CYP2A6ALDH5A1ABATKDM4E | |
| SCHEMBL97268 | 0.70 | ALDH1A1 (0.62) | ALDH1A1CYP2A6ALDH5A1ABATKDM4E | |
| SCHEMBL3113924 | 0.69 | KMT2A (0.59) | ALDH1A1KDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1457210-A1 | REMEDIES AND/OR PREVENTIVES FOR CONFORMATIONAL DISEASES | Itoham Foods Inc. (JP) | 2004-09-15 | — | — | EP | disclosed |
| US-20040132648-A1 | Remedies and/or preventives for conformational diseases | ITOHAM FOODS INC. (JP) | 2004-07-08 | — | — | US | disclosed |
| WO-1999064056-A9 | USE OF A CYTOKINE REGULATORY AGENT TO TREAT ASTHMA | TREGA BIOSCIENCES INC (US) | 2000-02-10 | — | — | WO | disclosed |
| WO-1999064056-A1 | USE OF A CYTOKINE REGULATORY AGENT TO TREAT ASTHMA | TREGA BIOSCIENCES, INC. (US) | 1999-12-16 | — | — | WO | disclosed |
| US-5741774-A | Use of a cytokine regulatory agent to treat rheumatoid arthritis | TREGA BIOSCIENCES, INC. (US) | 1998-04-21 | — | — | US | disclosed |
| WO-1998013060-A1 | USE OF A CYTOKINE REGULATORY AGENT TO TREAT RHEUMATOID ARTHRITIS | TREGA BIOSCIENCES, INC. (US) | 1998-04-02 | — | — | WO | disclosed |
| WO-1998013032-A1 | COMPOSITIONS OF THERAPEUTIC AGENTS SUITABLE FOR ORAL ADMINISTRATION | TREGA BIOSCIENCES, INC. (US) | 1998-04-02 | — | — | WO | disclosed |