Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | DRD1 | P21728 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6024591 | 0.88 | CHRM2 (0.44) | HPGDAOC3CHRM2HTR1AADRA2A | |
| SCHEMBL4155150 | 0.80 | TDP1 (0.40) | TP53ALDH1A1HPGDALOX15ALOX12 | |
| SCHEMBL28202908 | 0.80 | TDP1 (0.40) | TP53ALDH1A1HPGDALOX15ALOX12 | |
| SCHEMBL114790 | 0.79 | TP53 (0.37) | TP53ALDH1A1HPGDALOX15ALOX12 | |
| SCHEMBL6303238 | 0.78 | SLC6A2 (0.46) | TP53ALDH1A1TAAR1SLC6A2SMN1; SMN2 | |
| SCHEMBL6554382 | 0.78 | ALDH1A1 (0.42) | TP53ALDH1A1HPGDALOX15ALOX12 | |
| SCHEMBL11054827 | 0.78 | ALDH1A1 (0.39) | ALDH1A1TAAR1TDP1SMN1; SMN2 | |
| SCHEMBL11006769 | 0.77 | CALM1 (0.38) | TP53ALDH1A1HSD17B10CHRM2ADRA2A | |
| SCHEMBL28668278 | 0.76 | ALDH1A1 (0.43) | ALDH1A1TDP1SMN1; SMN2 | |
| SCHEMBL38652393 | 0.74 | MEN1 (0.40) | ALDH1A1SMN1; SMN2SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060106037-A1 | Purin-6-one-derivatives | ALTANA PHARMA AG (DE) | 2006-05-18 | — | — | US | disclosed |
| EP-1601675-A1 | PURIN-6-ONE-DERIVATIVES | ALTANA Pharma AG (DE) | 2005-12-07 | — | — | EP | disclosed |
| WO-2004089953-A1 | PURIN-6-ONE-DERIVATIVES | ALTANA PHARMA AG (DE) | 2004-10-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060106037-A1 | Purin-6-one-derivatives | PDE4B, PDE4A, PDE2A | TP53 4391/4885ALDH1A1 1366/4885HPGD 892/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.