Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | ELANE | P08246 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 2/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.34 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27988200 | 0.86 | THRB (0.40) | ALDH1A1THRB | |
| SCHEMBL27566734 | 0.84 | THRB (0.33) | THRB | |
| SCHEMBL8020679 | 0.82 | THRB (0.41) | ALDH1A1SMN1; SMN2MAPTRECQLTHRB | |
| SCHEMBL29023302 | 0.80 | ALDH1A1 (0.41) | ALDH1A1SMN1; SMN2MAPTELANEKMT2A | |
| SCHEMBL6546171 | 0.80 | ALDH1A1 (0.43) | ALDH1A1SMN1; SMN2ELANERECQLKMT2A | |
| SCHEMBL29023299 | 0.79 | ALDH1A1 (0.40) | ALDH1A1SMN1; SMN2MAPTELANEL3MBTL1 | |
| SCHEMBL6023404 | 0.78 | TP53 (0.41) | ALDH1A1SMN1; SMN2TAAR1TDP1 | |
| SCHEMBL8023838 | 0.78 | ALOX5 (0.36) | ALDH1A1SMN1; SMN2HDAC3HDAC4HDAC1 | |
| SCHEMBL6384935 | 0.77 | ALDH1A1 (0.41) | ALDH1A1SMN1; SMN2MAPTRECQLTHRB | |
| SCHEMBL27544033 | 0.76 | THRB (0.35) | THRBHTTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4454258-A | COPOLYMERS OF UNSATURATED ESTERS AS BINDERS FOR POWDERED FILLERS | KANEBO LTD. (JP) | 1984-06-12 | — | — | US | disclosed |
| US-4440878-A | NITRIDE AND BINDER BASED ON A PENTAERYTHRITOL ACRYLATE MONOMER; CURING; BONDING | KANEBO, LTD. (JP) | 1984-04-03 | — | — | US | disclosed |
| EP-0092260-A1 | A composition of restorative material | KANEBO, LTD. (JP) | 1983-10-26 | — | — | EP | disclosed |
| US-4327014-A | INORGANIC NITRIDE FILLERS IN BINDERS OF PENTAERYTHRITOL TRI-OR TETRA-ACRYLATES | KANEBO LTD. (JP) | 1982-04-27 | — | — | US | disclosed |
| EP-0017936-A2 | Compositions of restorative material especially suitable for dental filling material | KANEBO, LTD. (JP) | 1980-10-29 | — | — | EP | disclosed |