SCHEMBL6023672

SCHEMBL6023672

CCCCC[C@H](CN(O)C=O)C(=O)N(N)C(=O)N1CCN(C)CC1

nearest known ligand 0.41

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
HTR1A P08908 1/20 0.40
BMP1 P13497 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4582834 0.84 BMP1 (0.34) HTR1ABMP1
SCHEMBL4582846 0.84 BMP1 (0.34) HTR1ABMP1
SCHEMBL4582839 0.84 BMP1 (0.34) HTR1ABMP1
SCHEMBL4954420 0.79 LMNA (0.40)
SCHEMBL4954423 0.79 LMNA (0.40)
SCHEMBL6024579 0.78 BMP1 (0.39) BMP1
SCHEMBL6023923 0.77 BMP1 (0.41) BMP1
SCHEMBL6023663 0.74 BMP1 (0.37) BMP1
SCHEMBL6025846 0.74 BMP1 (0.37) BMP1
SCHEMBL6024312 0.74 BMP1 (0.37) BMP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1363873-A4 PEPTIDE DEFORMYLASE INHIBITORS SMITHKLINE BEECHAM CORP (US) 2006-01-04 EP disclosed
EP-1363873-A2 PEPTIDE DEFORMYLASE INHIBITORS SmithKline Beecham Corporation (US) 2003-11-26 EP disclosed
WO-2002070541-A2 PEPTIDE DEFORMYLASE INHIBITORS SMITH KLINE BEECHAM CORPORATION (US) 2002-09-12 WO disclosed