Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BMP1 | P13497 | 2/20 | 0.34 |
| ▸ | Q9HBH1 | 1/20 | 0.33 | |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4582839 | 1.00 | BMP1 (0.34) | BMP1PDFHTR1A | |
| SCHEMBL4582834 | 1.00 | BMP1 (0.34) | BMP1PDFHTR1A | |
| SCHEMBL4954420 | 0.84 | LMNA (0.40) | — | |
| SCHEMBL4954423 | 0.84 | LMNA (0.40) | — | |
| SCHEMBL6023672 | 0.84 | HTR1A (0.40) | BMP1HTR1A | |
| SCHEMBL1596215 | 0.77 | BMP1 (0.40) | BMP1PDF | |
| SCHEMBL1596205 | 0.77 | BMP1 (0.40) | BMP1PDF | |
| SCHEMBL1596212 | 0.77 | BMP1 (0.40) | BMP1PDF | |
| SCHEMBL6023923 | 0.75 | BMP1 (0.41) | BMP1 | |
| SCHEMBL14282181 | 0.74 | PDF (0.52) |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1509218-A4 | PEPTIDE DEFORMYLASE INHIBITORS | SMITHKLINE BEECHAM CORP (US) | 2008-03-26 | — | — | EP | disclosed |
| EP-1509218-A1 | PEPTIDE DEFORMYLASE INHIBITORS | SmithKline Beecham Corporation (US) | 2005-03-02 | — | — | EP | disclosed |
| WO-2003101442-A1 | PEPTIDE DEFORMYLASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2003-12-11 | — | — | WO | disclosed |