Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BMP1 | P13497 | 7/20 | 0.47 |
| ▸ | CTSK | P43235 | 2/20 | 0.41 |
| ▸ | MMP12 | P39900 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6023686 | 0.85 | BMP1 (0.38) | BMP1MMP12 | |
| SCHEMBL6023680 | 0.81 | PDF (0.38) | BMP1MMP12 | |
| SCHEMBL6024335 | 0.80 | PDF (0.37) | BMP1MMP12 | |
| SCHEMBL4961871 | 0.79 | BMP1 (0.51) | BMP1MMP12 | |
| SCHEMBL6025314 | 0.79 | MTNR1A (0.47) | — | |
| SCHEMBL4958164 | 0.78 | BMP1 (0.50) | BMP1CTSKMMP12 | |
| SCHEMBL6024633 | 0.77 | BMP1 (0.47) | BMP1MMP12 | |
| SCHEMBL1595893 | 0.75 | BMP1 (0.57) | BMP1MMP12 | |
| SCHEMBL1595891 | 0.75 | BMP1 (0.57) | BMP1MMP12 | |
| SCHEMBL1595896 | 0.75 | BMP1 (0.57) | BMP1MMP12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1363873-A4 | PEPTIDE DEFORMYLASE INHIBITORS | SMITHKLINE BEECHAM CORP (US) | 2006-01-04 | — | — | EP | disclosed |
| EP-1363873-A2 | PEPTIDE DEFORMYLASE INHIBITORS | SmithKline Beecham Corporation (US) | 2003-11-26 | — | — | EP | disclosed |
| WO-2002070541-A2 | PEPTIDE DEFORMYLASE INHIBITORS | SMITH KLINE BEECHAM CORPORATION (US) | 2002-09-12 | — | — | WO | disclosed |