Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.59 |
| ▸ | TP53 | P04637 | 3/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.51 |
| ▸ | LMNA | P02545 | 6/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | JAK2 | O60674 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.46 |
| ▸ | HTR6 | P50406 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5761601 | 0.90 | MAPT (0.51) | MAPTTP53KMT2ALMNAALDH1A1 | |
| SCHEMBL6023175 | 0.88 | KMT2A (0.52) | KMT2AALDH1A1THRBSMN1; SMN2MEN1 | |
| SCHEMBL6023752 | 0.83 | SMN1; SMN2 (0.56) | MAPTTP53LMNATHRBSMN1; SMN2 | |
| SCHEMBL6022246 | 0.83 | TP53 (0.58) | MAPTTP53KMT2ALMNAALDH1A1 | |
| SCHEMBL1770881 | 0.79 | AR (0.61) | MAPTKMT2AALDH1A1TSHRMEN1 | |
| SCHEMBL6022360 | 0.77 | POLB (0.53) | MAPTTP53 | |
| SCHEMBL6022312 | 0.76 | POLB (0.48) | MAPTTP53KMT2ALMNA | |
| SCHEMBL6022657 | 0.76 | PKM (0.49) | TP53KMT2AMEN1GAA | |
| SCHEMBL6023629 | 0.76 | PKM (0.57) | TSHRTHRBSMN1; SMN2GAA | |
| SCHEMBL6022243 | 0.76 | AR (0.61) | MAPTTP53KMT2ALMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7009052-B2 | Sulfonamide derivatives | WARNER LAMBERT COMPANY LLC (US) | 2006-03-07 | — | — | US | disclosed |