Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOS1 | Q07889 | 1/20 | 0.48 |
| ▸ | MAPK14 | Q16539 | 9/20 | 0.45 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.41 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.41 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | TDO2 | P48775 | 1/20 | 0.40 |
| ▸ | APP | P05067 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL96822 | 0.77 | CYP11B2 (0.36) | — | |
| SCHEMBL15515147 | 0.72 | MAPT (0.53) | SOS1MAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL27145735 | 0.71 | SOS1 (0.50) | SOS1MAPK14CNR1CNR2APP | |
| SCHEMBL22563177 | 0.71 | LRRK2 (0.42) | MAPK14CNR1CNR2 | |
| SCHEMBL21468597 | 0.70 | SOS1 (0.53) | SOS1MAPK14APPMAPT | |
| SCHEMBL12483334 | 0.70 | LMNA (0.51) | SOS1MAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL96914 | 0.69 | CES2 (0.43) | IDO1 | |
| SCHEMBL2199363 | 0.69 | MAPK14 (0.56) | SOS1MAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL7232413 | 0.69 | SLC22A12 (0.37) | IDO1 | |
| SCHEMBL28924001 | 0.67 | SOS1 (0.63) | SOS1MAPK14CNR1CNR2APP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1658263-A1 | NOVEL AMINOBENZOPHENONE COMPOUNDS | Leo Pharma A/S (DK) | 2006-05-24 | — | — | EP | disclosed |
| WO-2005009940-A1 | NOVEL AMINOBENZOPHENONE COMPOUNDS | LEO PHARMA A/S (DK) | 2005-02-03 | — | — | WO | disclosed |