SCHEMBL6023958

SCHEMBL6023958

CO[C@@H]1[C@@H](OS(=O)(=O)O)[C@@H](O)O[C@H](COS(=O)(=O)O)[C@H]1O[C@@H]1O[C@@H](C(=O)O)[C@@H](O)[C@H](O)[C@H]1OC

nearest known ligand 0.58

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
SERPINC1 P01008 4/20 0.58
F10 P00742 7/20 0.54
BDNF P23560 3/20 0.45
PTN P21246 2/20 0.45
MDK P21741 2/20 0.45
FGF1 P05230 4/20 0.43
FGF2 P09038 1/20 0.41
CXCL10 P02778 1/20 0.41
CXCL8 P10145 1/20 0.41
CCL2 P13500 1/20 0.41
CCL5 P13501 1/20 0.41
CXCL12 P48061 1/20 0.41
F2 P00734 2/20 0.38
HPSE Q9Y251 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15417563 0.84 F10 (0.53) SERPINC1F10BDNFPTNMDK
SCHEMBL27448112 0.80 BDNF (0.60) SERPINC1F10BDNFPTNMDK
SCHEMBL29407493 0.80 SERPINC1 (0.85) SERPINC1F10BDNFPTNMDK
Idraparinux SCHEMBL427808 0.80 SERPINC1 (0.85) SERPINC1F10BDNFPTNMDK
Idraparinux SCHEMBL29382311 0.80 SERPINC1 (0.85) SERPINC1F10BDNFPTNMDK
SCHEMBL20149721 0.80 F10 (0.52) SERPINC1F10BDNFPTNMDK
SCHEMBL14670002 0.80 F10 (0.64) SERPINC1F10BDNFPTNMDK
SCHEMBL13311345 0.80 F10 (0.64) SERPINC1F10BDNFPTNMDK
SCHEMBL4593793 0.80 F10 (0.64) SERPINC1F10BDNFPTNMDK
SCHEMBL16656905 0.79 F10 (0.63) SERPINC1F10BDNFPTNMDK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1725577-A1 ANTITHROMBOTIC COMPOUND Sanofi-Aventis (FR) 2006-11-29 EP disclosed
WO-2005090382-A1 ANTITHROMBOTIC COMPOUND SANOFI-AVENTIS (FR) 2005-09-29 WO disclosed