SCHEMBL6024142

SCHEMBL6024142

CCCc1ccccc1N.Cc1ccc(N)c(C)c1C

nearest known ligand 0.39

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 2/20 0.39
TSHR P16473 1/20 0.39
PIK3CA P42336 1/20 0.39
TDP1 Q9NUW8 1/20 0.36
TAAR1 Q96RJ0 1/20 0.36
SKP2 Q13309 1/20 0.35
SIGMAR1 Q99720 2/20 0.34
ALDH1A1 P00352 2/20 0.33
ATP4A P20648 1/20 0.33
ATP4B P51164 1/20 0.33
KDM4E B2RXH2 2/20 0.33
HPGD P15428 1/20 0.33
POLB P06746 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP2C9 P11712 1/20 0.33
CYP2C19 P33261 1/20 0.33
NOS2 P35228 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29443967 0.83 CYP3A4 (0.43) CYP3A4TSHRPIK3CATDP1TAAR1
SCHEMBL43944 0.83 CYP3A4 (0.43) CYP3A4TSHRPIK3CATDP1TAAR1
Hydrochloric Acid SCHEMBL9834388 0.81 CYP3A4 (0.42) CYP3A4TDP1TAAR1SIGMAR1ALDH1A1
Dimethylamine SCHEMBL11264463 0.77 SIGMAR1 (0.39) CYP3A4TDP1TAAR1SIGMAR1ALDH1A1
SCHEMBL9174323 0.75 CYP3A4 (0.42) CYP3A4TSHRPIK3CATDP1TAAR1
SCHEMBL8942955 0.74 ALDH1A1 (0.41) CYP3A4TSHRTDP1TAAR1ALDH1A1
Catechol SCHEMBL11031358 0.74 TSHR (0.48) CYP3A4TSHRPIK3CATDP1TAAR1
SCHEMBL33509 0.74 CYP3A4 (0.50) CYP3A4TSHRPIK3CATDP1ALDH1A1
Ammonia Solution, Strong SCHEMBL28700970 0.74 SKP2 (0.37) CYP3A4TSHRPIK3CATDP1SKP2
Alcohol SCHEMBL239141 0.73 CYP3A4 (0.40) CYP3A4TSHRPIK3CATDP1SKP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1628160-A2 Resist composition and patterning process Shin-Etsu Chemical Co., Ltd. (JP) 2006-02-22 EP disclosed