Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 5/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | CNR1 | P21554 | 3/20 | 0.37 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL667595 | 0.87 | LMNA (0.43) | LMNAPOLBTP53MAPTMEN1 | |
| SCHEMBL663113 | 0.76 | NPC1 (0.57) | LMNAPOLBTP53MAPTMEN1 | |
| SCHEMBL2011767 | 0.73 | SMN1; SMN2 (0.52) | LMNATP53MAPTMEN1KMT2A | |
| SCHEMBL659925 | 0.72 | KDM4E (0.47) | LMNAMAPTCRHR1NPY5R | |
| SCHEMBL661172 | 0.72 | CRHR1 (0.43) | MAPTMEN1KMT2ACRHR1THRB | |
| SCHEMBL29868397 | 0.72 | PKM (0.48) | LMNATP53MAPTMEN1KMT2A | |
| SCHEMBL663000 | 0.72 | PKM (0.48) | LMNATP53MAPTMEN1KMT2A | |
| SCHEMBL664081 | 0.72 | NPC1 (0.49) | LMNATP53MAPTMEN1KMT2A | |
| SCHEMBL2853159 | 0.71 | KDM4E (0.43) | TP53MAPTCRHR1THRBNPY5R | |
| SCHEMBL662812 | 0.71 | ALDH1A1 (0.53) | LMNAKMT2ACNR1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1620399-A1 | INDOLONE-ACETAMIDE DERIVATIVES, PROCESSES FOR PREPARING THEM AND THEIR USES | UCB, S.A. (BE) | 2006-02-01 | — | — | EP | claimed |
| WO-2004087658-A1 | INDOLONE-ACETAMIDE DERIVATIVES, PROCESSES FOR PREPARING THEM AND THEIR USES | UCB, S.A. (BE) | 2004-10-14 | — | — | WO | claimed |