Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | AHR | P35869 | 1/20 | 0.36 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | HK1 | P19367 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | GALK1 | P51570 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15196679 | 0.69 | MAPT (0.56) | SRCMEN1MAPTKMT2AKDM4E | |
| SCHEMBL88280 | 0.69 | MAPT (0.47) | SRCMEN1MAPTKMT2AKDM4E | |
| SCHEMBL29896031 | 0.69 | MAPT (0.47) | SRCMEN1MAPTKMT2AKDM4E | |
| SCHEMBL29757969 | 0.68 | NPC1 (0.50) | SRCMEN1MAPTKMT2AKDM4E | |
| SCHEMBL6024420 | 0.67 | ALDH1A1 (0.36) | MAPTKMT2AKDM4EGAATDP1 | |
| SCHEMBL16470043 | 0.66 | HSD17B10 (0.42) | MEN1MAPTKMT2AKDM4ENPC1 | |
| SCHEMBL25275193 | 0.65 | MAPT (0.47) | SRCMEN1MAPTKMT2AKDM4E | |
| SCHEMBL7516634 | 0.65 | MEN1 (0.47) | SRCMEN1MAPTKMT2AKDM4E | |
| SCHEMBL16470683 | 0.65 | MEN1 (0.50) | MEN1KMT2AKDM4EPOLBNOX1 | |
| SCHEMBL5141694 | 0.65 | NPC1 (0.47) | SRCMEN1MAPTKMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1353908-B1 | PROCESSES AND SYNTHETIC INTERMEDIATES FOR PREPARING N-ARYLACRIDANCARBOXYLIC ACID DERIVATIVES | LUMIGEN INC (US) | 2006-03-08 | — | — | EP | disclosed |
| EP-1353908-A4 | PROCESSES AND SYNTHETIC INTERMEDIATES FOR PREPARING N-ARYLACRIDANCARBOXYLIC ACID DERIVATIVES | LUMIGEN INC (US) | 2004-01-28 | — | — | EP | disclosed |
| EP-1353908-A1 | PROCESSES AND SYNTHETIC INTERMEDIATES FOR PREPARING N-ARYLACRIDANCARBOXYLIC ACID DERIVATIVES | LUMIGEN, INC. (US) | 2003-10-22 | — | — | EP | disclosed |
| WO-2002059096-A1 | PROCESSES AND SYNTHETIC INTERMEDIATES FOR PREPARING N-ARYLACRIDANCARBOXYLIC ACID DERIVATIVES | LUMIGEN, INC. (US) | 2002-08-01 | — | — | WO | disclosed |
| US-6410732-B2 | FORMATION OF BOND BETWEEN NITROGEN ATOM OF ACRIDAN RING AND CARBON ATOM OF ANOTHER AROMATIC OR HETEROAROMATIC RING COMPOUND; ASSAYS FOR PEROXIDASE ENZYMES AND ENZYME INHIBITORS AND IN ASSAYS EMPLOYING ENZYME-LABELED SPECIFIC BINDING PAIRS | LUMIGEN, INC. | 2002-06-25 | — | — | US | disclosed |
| US-20010031869-A1 | Processes and synthetic intermediates for preparing N-arylacridancarboxylic acid derivatives | LUMIGEN, INC. | 2001-10-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010031869-A1 | Processes and synthetic intermediates for preparing N-arylacridancarboxylic acid derivatives | ALDH3A1, AADAC, SPR | SRC 2615/4885MEN1 4540/4885MAPT 4271/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.