Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | MGLL | Q99685 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 2/20 | 0.37 |
| ▸ | PPARA | Q07869 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11773570 | 0.81 | NPSR1 (0.36) | GAAKMT2AMAPK1NPSR1MAPT | |
| SCHEMBL15389722 | 0.81 | NPSR1 (0.36) | GAAKMT2AMAPK1NPSR1MAPT | |
| SCHEMBL11773577 | 0.81 | NPSR1 (0.36) | GAAKMT2AMAPK1NPSR1MAPT | |
| SCHEMBL6024791 | 0.79 | GAA (0.39) | GAAALDH1A1KMT2ANPSR1MAPT | |
| SCHEMBL6024796 | 0.79 | GAA (0.39) | GAAALDH1A1KMT2ANPSR1MAPT | |
| SCHEMBL213778 | 0.78 | MAPT (0.55) | GAAALDH1A1KMT2AMAPK1NPSR1 | |
| SCHEMBL36190 | 0.78 | PLA2G7 (0.46) | GAAALDH1A1MAPK1NPSR1MAPT | |
| SCHEMBL12629321 | 0.78 | CES2 (0.43) | GAAALDH1A1KMT2ANPSR1MAPT | |
| SCHEMBL295508 | 0.78 | PLA2G7 (0.46) | GAAALDH1A1MAPK1NPSR1MAPT | |
| SCHEMBL10182710 | 0.78 | CES2 (0.47) | ALDH1A1KMT2AMAPK1NPSR1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11767291-B2 | Preparation of secondary amines with electrophilic N-linchpin reagents | WILLIAM MARSH RICE UNIVERSITY (US) | 2023-09-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11767291-B2 | Preparation of secondary amines with electrophilic N-linchpin reagents | PNMT, NCL, NPM1 | GAA 3549/4885ALDH1A1 1805/4885KMT2A 127/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.