SCHEMBL6025191

SCHEMBL6025191

O=C(O)C(=O)c1ccc2c(c1)Sc1ccccc1S2

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NOX1 Q9Y5S8 4/20 0.42
MAPT P10636 3/20 0.42
MEN1 O00255 1/20 0.42
CYBB P04839 1/20 0.42
APP P05067 1/20 0.42
GAA P10253 1/20 0.42
ALOX15 P16050 1/20 0.42
SNCA P37840 1/20 0.42
KMT2A Q03164 1/20 0.42
NOX3 Q9HBY0 1/20 0.42
NOX4 Q9NPH5 1/20 0.42
PLEC Q15149 1/20 0.42
CPT1B Q92523 1/20 0.42
LMNA P02545 1/20 0.41
MAPK1 P28482 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
CES2 O00748 5/20 0.41
CES1 P23141 5/20 0.41
BCHE P06276 4/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30944690 0.84 PLEC (0.51) NOX1MAPTMEN1CYBBAPP
SCHEMBL2639219 0.84 PLEC (0.51) NOX1MAPTMEN1CYBBAPP
SCHEMBL11823817 0.84 CES2 (0.41) NOX1MEN1GAAKMT2ACPT1B
SCHEMBL11823896 0.81 NOX1 (0.41) NOX1MAPTMEN1CYBBAPP
SCHEMBL6025577 0.80 GAA (0.42) NOX1MAPTMEN1CYBBAPP
SCHEMBL6025574 0.80 GAA (0.42) NOX1MAPTMEN1CYBBAPP
SCHEMBL11825224 0.80 ALOX5 (0.41) MEN1KMT2APLECCPT1BBCHE
SCHEMBL11823612 0.80 ALDH1A1 (0.46) NOX1MAPTMEN1CYBBAPP
SCHEMBL11827768 0.79 NOX1 (0.42) NOX1MAPTMEN1CYBBAPP
SCHEMBL11827754 0.79 NOX1 (0.42) NOX1MAPTMEN1CYBBAPP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1163553-B1 OXIME DERIVATIVES AND THE USE THEREOF AS PHOTOINITIATORS CIBA SC HOLDING AG (CH) 2006-06-14 EP disclosed
EP-1635220-A2 Oxime derivatives and the use thereof as photoinitiators Ciba Specialty Chemicals Holding Inc. (CH) 2006-03-15 EP disclosed
US-6806024-B1 MIXTURES OF ADDITION POLYMERS AND ACTIVATORS COMPRISING NITROGEN COMPOUNDS, USED AS SUBSTRATE COATINGS FOR COLOR FILTERS CIBA SPECIALTY CHEMICALS CORPORATION 2004-10-19 US disclosed
EP-1163553-A1 OXIME DERIVATIVES AND THE USE THEREOF AS PHOTOINITIATORS Ciba SC Holding AG (CH) 2001-12-19 EP disclosed
WO-2000052530-A1 OXIME DERIVATIVES AND THE USE THEREOF AS PHOTOINITIATORS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2000-09-08 WO disclosed
US-3975403-A Sulfur-containing ring compounds MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) 1976-08-17 US disclosed