Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 12/20 | 0.48 |
| ▸ | OPRK1 | P41145 | 11/20 | 0.48 |
| ▸ | OPRL1 | P41146 | 11/20 | 0.48 |
| ▸ | OPRD1 | P41143 | 10/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.42 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.42 |
| ▸ | DRD1 | P21728 | 1/20 | 0.42 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | HRH1 | P35367 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
| ▸ | HTR2B | P41595 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29046178 | 0.90 | OPRM1 (0.42) | OPRM1OPRK1OPRL1OPRD1CYP2D6 | |
| SCHEMBL9792723 | 0.76 | OPRM1 (0.51) | OPRM1OPRK1OPRL1OPRD1CYP2D6 | |
| SCHEMBL13163119 | 0.76 | OPRM1 (0.51) | OPRM1OPRK1OPRL1OPRD1CYP2D6 | |
| SCHEMBL21787342 | 0.76 | OPRM1 (0.51) | OPRM1OPRK1OPRL1OPRD1CYP2D6 | |
| SCHEMBL11479004 | 0.75 | OPRM1 (0.55) | OPRM1OPRK1OPRL1OPRD1CYP2D6 | |
| SCHEMBL9684657 | 0.75 | OPRM1 (0.45) | OPRM1OPRK1OPRL1OPRD1KMT2A | |
| SCHEMBL5368864 | 0.72 | OPRM1 (0.47) | OPRM1OPRK1OPRL1OPRD1CYP2D6 | |
| SCHEMBL11461772 | 0.71 | OPRM1 (0.55) | OPRM1OPRK1OPRL1OPRD1CYP2D6 | |
| Methane SCHEMBL11728059 | 0.70 | OPRM1 (0.50) | OPRM1OPRK1OPRL1OPRD1CYP2D6 | |
| SCHEMBL9359382 | 0.70 | OPRD1 (0.46) | OPRM1OPRK1OPRL1OPRD1CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1638570-A1 | PYRIMIDINE DERIVATIVES AS CANNABINOID RECEPTOR LIGANDS | Pfizer Products Inc. (US) | 2006-03-29 | — | — | EP | disclosed |
| WO-2004110453-A1 | PYRIMIDINE DERIVATIVES AS CANNABINOID RECEPTOR LIGANDS | PFIZER PRODUCTS INC. (US) | 2004-12-23 | — | — | WO | disclosed |