Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 8/20 | 0.45 |
| ▸ | OPRD1 | P41143 | 8/20 | 0.45 |
| ▸ | OPRK1 | P41145 | 8/20 | 0.45 |
| ▸ | OPRL1 | P41146 | 8/20 | 0.45 |
| ▸ | XIAP | P98170 | 5/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6025516 | 0.75 | OPRM1 (0.48) | OPRM1OPRD1OPRK1OPRL1KMT2A | |
| SCHEMBL2770710 | 0.69 | KMT2A (0.48) | OPRM1OPRD1OPRK1OPRL1KMT2A | |
| SCHEMBL5685739 | 0.68 | ALDH1A1 (0.47) | OPRM1OPRD1OPRK1OPRL1HTT | |
| SCHEMBL5685826 | 0.68 | ALDH1A1 (0.47) | OPRM1OPRD1OPRK1OPRL1HTT | |
| SCHEMBL5685743 | 0.68 | ALDH1A1 (0.47) | OPRM1OPRD1OPRK1OPRL1HTT | |
| SCHEMBL10783873 | 0.68 | OPRM1 (0.46) | OPRM1OPRD1OPRK1OPRL1HTT | |
| SCHEMBL4848461 | 0.67 | SIGMAR1 (0.65) | KMT2A | |
| SCHEMBL9194851 | 0.66 | CTSD (0.58) | HTTNPSR1GAACTRB1KMT2A | |
| SCHEMBL9194859 | 0.66 | CTSD (0.58) | HTTNPSR1GAACTRB1KMT2A | |
| SCHEMBL29046178 | 0.66 | OPRM1 (0.42) | OPRM1OPRD1OPRK1OPRL1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0514268-A1 | Substituted amino acid azetidinyl pyridone derivatives, their preparation and use as medicines | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 1992-11-19 | — | — | EP | disclosed |