Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 2/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | CES2 | O00748 | 1/20 | 0.43 |
| ▸ | USP14 | P54578 | 1/20 | 0.42 |
| ▸ | RYR2 | Q92736 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.39 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27905740 | 0.86 | CNR2 (0.41) | CNR2POLBMEN1KMT2AHSD17B10 | |
| SCHEMBL8668045 | 0.79 | POLB (0.46) | POLBMEN1KMT2AHSD17B10ALDH1A1 | |
| SCHEMBL2004993 | 0.79 | CNR2 (0.66) | CNR2MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL8579955 | 0.77 | LMNA (0.65) | MEN1KMT2AKDM4EMAPTHTT | |
| SCHEMBL5822660 | 0.75 | AKR1C3 (0.65) | MEN1KMT2AKDM4EMAPTRAB9A | |
| SCHEMBL1076364 | 0.75 | PTGS2 (0.65) | CNR2MEN1KMT2AKDM4EMAPT | |
| SCHEMBL3240338 | 0.74 | PTGS1 (0.48) | CNR2POLBMEN1KMT2AKDM4E | |
| SCHEMBL3252299 | 0.74 | CNR2 (0.56) | CNR2POLBMEN1KMT2AHPGD | |
| SCHEMBL11436509 | 0.74 | PTGS2 (0.64) | CNR2MEN1KMT2AKDM4EMAPT | |
| SCHEMBL5799148 | 0.73 | PTGS2 (0.52) | CNR2MEN1KMT2AKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1628532-A2 | METHODS FOR THE PROTECTION OF MEMORY AND COGNITION | Microbia, Inc. (US) | 2006-03-01 | — | — | EP | claimed |
| WO-2004108085-A2 | METHODS FOR THE PROTECTION OF MEMORY AND COGNITION | MICROBIA, INC. (US) | 2004-12-16 | — | — | WO | claimed |
| EP-1628532-A2 | METHODS FOR THE PROTECTION OF MEMORY AND COGNITION | Microbia, Inc. (US) | 2006-03-01 | — | — | EP | disclosed |
| WO-2004108085-A2 | METHODS FOR THE PROTECTION OF MEMORY AND COGNITION | MICROBIA, INC. (US) | 2004-12-16 | — | — | WO | disclosed |