Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 4/20 | 0.41 |
| ▸ | AKR1C2 | P52895 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8673753 | 0.85 | HTR6 (0.43) | POLBHTTMAPTHSD17B10MEN1 | |
| SCHEMBL31370521 | 0.81 | KDM4E (0.43) | HTTMAPTMEN1KMT2AKDM4E | |
| SCHEMBL18919047 | 0.80 | KDM4E (0.42) | HTTMAPTMEN1KMT2AKDM4E | |
| SCHEMBL6026089 | 0.79 | CNR2 (0.56) | POLBHTTMAPTHSD17B10MEN1 | |
| SCHEMBL8579955 | 0.79 | LMNA (0.65) | HTTMAPTMEN1KMT2AKDM4E | |
| SCHEMBL2073076 | 0.78 | AKR1C3 (0.68) | MAPTMEN1KMT2AKDM4EAKR1C3 | |
| SCHEMBL1076364 | 0.77 | PTGS2 (0.65) | MAPTMEN1KMT2AKDM4EAKR1C3 | |
| SCHEMBL5822660 | 0.77 | AKR1C3 (0.65) | MAPTMEN1KMT2AKDM4EAKR1C3 | |
| SCHEMBL5554095 | 0.77 | AKR1C3 (0.56) | MAPTMEN1KMT2AKDM4EAKR1C3 | |
| SCHEMBL3240338 | 0.76 | PTGS1 (0.48) | POLBMAPTMEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5750558-A | ANTIALLERGENS, ANTIINFLAMMATORY AGENTS | ABBOTT LABORATORIES (US) | 1998-05-12 | — | — | US | disclosed |