Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.36 |
| ▸ | MEN1 | O00255 | 6/20 | 0.36 |
| ▸ | NPC1 | O15118 | 4/20 | 0.36 |
| ▸ | RAB9A | P51151 | 4/20 | 0.36 |
| ▸ | POLB | P06746 | 4/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.35 |
| ▸ | MAPT | P10636 | 9/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | APEX1 | P27695 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6026335 | 0.82 | MEN1 (0.53) | GPR84FFAR1KMT2AMEN1NPC1 | |
| SCHEMBL6025034 | 0.79 | NPC1 (0.43) | KMT2AMEN1NPC1RAB9APOLB | |
| SCHEMBL4699425 | 0.70 | RXFP3 (0.42) | KMT2AMEN1NPC1RAB9APOLB | |
| SCHEMBL6026134 | 0.70 | MEN1 (0.50) | KMT2AMEN1NPC1RAB9APOLB | |
| SCHEMBL4699467 | 0.67 | RXFP3 (0.45) | KMT2AMEN1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL14145831 | 0.63 | GPR84 (0.75) | GPR84FFAR1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL6026142 | 0.61 | RXFP3 (0.53) | KMT2AMEN1NPC1RAB9APOLB | |
| SCHEMBL6026757 | 0.61 | MAPT (0.69) | KMT2AMEN1NPC1RAB9APOLB | |
| SCHEMBL6026750 | 0.61 | MAPT (0.69) | KMT2AMEN1NPC1RAB9APOLB | |
| SCHEMBL11311801 | 0.60 | GPR84 (0.71) | GPR84FFAR1KMT2AMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7153881-B2 | Compounds acting as melanocortin receptor ligands | ACURE PHARMA AB (SE) | 2006-12-26 | — | — | US | claimed |
| US-7153881-B2 | Compounds acting as melanocortin receptor ligands | ACURE PHARMA AB (SE) | 2006-12-26 | — | — | US | disclosed |