Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 2/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.40 |
| ▸ | TACR2 | P21452 | 2/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | SHBG | P04278 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.40 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28547883 | 0.70 | SPHK1 (0.38) | ALDH1A1HSD17B10HPGDCA2CA1 | |
| SCHEMBL83869 | 0.66 | CA2 (0.65) | ALDH1A1LMNAHSD17B10HPGDESR1 | |
| SCHEMBL28550292 | 0.66 | PLA2G6 (0.42) | ALDH1A1SLC6A3TP53CA2 | |
| SCHEMBL10692168 | 0.66 | CYP1A2 (0.43) | ALDH1A1HSD17B10HPGDTP53CA2 | |
| SCHEMBL20233 | 0.65 | ESR1 (0.83) | ALDH1A1LMNAHSD17B10HPGDESR1 | |
| Formaldehyde SCHEMBL305916 | 0.64 | ESR1 (0.73) | ALDH1A1LMNAHSD17B10HPGDESR1 | |
| Ammonia Solution, Strong SCHEMBL28990998 | 0.64 | CA2 (0.62) | ALDH1A1LMNAHSD17B10HPGDESR1 | |
| SCHEMBL9839955 | 0.64 | CA2 (0.62) | ALDH1A1LMNAHSD17B10HPGDESR1 | |
| SCHEMBL10568421 | 0.64 | ALDH1A1 (0.65) | ALDH1A1LMNAHSD17B10HPGDESR1 | |
| SCHEMBL10720546 | 0.64 | THRA (0.47) | ALDH1A1LMNAHSD17B10HPGDESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6010685-A | SUNSCREEN AGENTS | OXIS INTERNATIONAL, INC. (US) | 2000-01-04 | — | — | US | claimed |
| US-7019029-B2 | Skin whiteners containing hydroxytetronic acid derivatives | THE NORTHWESTERN MUTUAL LIFE INSURANCE COMPANY, AS ADMINISTRATIVE AGENT | 2006-03-28 | — | — | US | disclosed |
| US-20020141956-A1 | Skin whiteners containing hydroxytetronic acid derivatives | THE NORTHWESTERN MUTUAL LIFE INSURANCE COMPANY, AS ADMINISTRATIVE AGENT | 2002-10-03 | — | — | US | disclosed |
| US-6010685-A | SUNSCREEN AGENTS | OXIS INTERNATIONAL, INC. (US) | 2000-01-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020141956-A1 | Skin whiteners containing hydroxytetronic acid derivatives | TYR, PPP6C, CYP26A1 | ALDH1A1 55/4885LMNA 3638/4885HSD17B10 132/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.