Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MASP2 | O00187 | 1/20 | 0.46 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.46 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | PLAU | P00749 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
| ▸ | FABP6 | P51161 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | CASP6 | P55212 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | NT5E | P21589 | 1/20 | 0.41 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.41 |
| ▸ | HTR3B | O95264 | 1/20 | 0.41 |
| ▸ | HTR3A | P46098 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10969202 | 0.83 | FABP6 (0.47) | ALDH1A1MEN1KMT2AMASP2NUDT1 | |
| SCHEMBL828238 | 0.83 | HDAC6 (0.59) | ALDH1A1MEN1KMT2AHDAC6HSD17B10 | |
| SCHEMBL1160168 | 0.80 | HDAC6 (0.46) | ALDH1A1MEN1KMT2AHDAC6HSD17B10 | |
| SCHEMBL4318643 | 0.80 | HDAC6 (0.46) | ALDH1A1MEN1KMT2AHDAC6HSD17B10 | |
| SCHEMBL4674386 | 0.80 | HDAC6 (0.46) | ALDH1A1MEN1KMT2AHDAC6HSD17B10 | |
| SCHEMBL21126954 | 0.80 | CACNA1H (0.44) | ALDH1A1MEN1KMT2AHDAC6HSD17B10 | |
| SCHEMBL28236381 | 0.79 | ALDH1A1 (0.56) | ALDH1A1MEN1KMT2AHDAC6HSD17B10 | |
| SCHEMBL10770660 | 0.79 | LMNA (0.45) | ALDH1A1KMT2AHDAC6HSD17B10ENPP2 | |
| Water SCHEMBL28362650 | 0.79 | HDAC6 (0.44) | ALDH1A1MEN1KMT2AHDAC6HSD17B10 | |
| SCHEMBL2817420 | 0.79 | HDAC6 (0.44) | ALDH1A1MEN1KMT2AHDAC6HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7122559-B2 | Phenylglycine derivatives useful as serine protease inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2006-10-17 | — | — | US | claimed |
| US-20040204412-A1 | Phenylglycine derivatives useful as serine protease inhibitors | BRISTOL-MYERS SQUIBB COMPANY | 2004-10-14 | — | — | US | claimed |
| US-7981205-B2 | Dye compound and ink containing dye compound | CANON KABUSHIKI KAISHA (JP) | 2011-07-19 | — | — | US | disclosed |
| US-20090293764-A1 | DYE COMPOUND AND INK CONTAINING DYE COMPOUND | CANON KABUSHIKI KAISHA (JP) | 2009-12-03 | — | — | US | disclosed |
| US-7122559-B2 | Phenylglycine derivatives useful as serine protease inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2006-10-17 | — | — | US | disclosed |
| US-20040204412-A1 | Phenylglycine derivatives useful as serine protease inhibitors | BRISTOL-MYERS SQUIBB COMPANY | 2004-10-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040204412-A1 | Phenylglycine derivatives useful as serine protease inhibitors | F7, SERPINE1, HABP2 | ALDH1A1 3767/4885MEN1 4047/4885KMT2A 1933/4885 |
| US-20090293764-A1 | DYE COMPOUND AND INK CONTAINING DYE COMPOUND | RB1, CRKL, TYR | ALDH1A1 170/4885MEN1 863/4885KMT2A 1444/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.