Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | SNCA | P37840 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17089134 | 0.87 | HDAC6 (0.60) | HDAC6TDP1HSP90AA1ESR2GAA | |
| SCHEMBL8501874 | 0.85 | NPBWR1 (0.47) | TDP1HSP90AA1ESR2MEN1KMT2A | |
| SCHEMBL14493326 | 0.83 | MAPT (0.51) | TDP1HSP90AA1ESR2HSD17B10MEN1 | |
| SCHEMBL828238 | 0.83 | HDAC6 (0.59) | HDAC6TDP1GAAHSD17B10MEN1 | |
| Hydrochloric Acid SCHEMBL32662723 | 0.82 | ALDH1A1 (0.44) | TDP1HSP90AA1ESR2GAAHSD17B10 | |
| SCHEMBL11371864 | 0.81 | TAS2R14 (0.54) | TDP1HSP90AA1ESR2GAAMEN1 | |
| SCHEMBL4674386 | 0.80 | HDAC6 (0.46) | HDAC6TDP1GAAHSD17B10MEN1 | |
| SCHEMBL6027004 | 0.80 | ALDH1A1 (0.46) | HDAC6TDP1HSD17B10MEN1KMT2A | |
| SCHEMBL1160168 | 0.80 | HDAC6 (0.46) | HDAC6TDP1GAAHSD17B10MEN1 | |
| SCHEMBL1108964 | 0.80 | TYMS (0.48) | TDP1HSP90AA1ESR2HSD17B10MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10738205-B2 | Polymerizable photoinitiators | AGFA NV (BE) | 2020-08-11 | — | — | US | disclosed |
| EP-3421547-A1 | COLORING COMPOSITION, INKJET RECORDING INK, INKJET RECORDING METHOD, AND INKJET PRINTER CARTRIDGE | FUJIFILM Corporation (JP) | 2019-01-02 | — | — | EP | disclosed |
| US-9982072-B2 | Synthesis of acetal compounds | AGFA NV (BE) | 2018-05-29 | — | — | US | disclosed |
| US-20160237185-A1 | SYNTHESIS OF ACETAL COMPOUNDS | AGFA NV (BE) | 2016-08-18 | — | — | US | disclosed |
| US-7569688-B2 | Propane-1, 3-dione derivative | ASTELLAS PHARMA INC. (JP) | 2009-08-04 | — | — | US | disclosed |
| US-20080293745-A1 | New amino-alkyl-amide derivatives as CCR3 receptor ligands | SANOFI-AVENTIS (FR) | 2008-11-27 | — | — | US | disclosed |
| US-20080293745-A1 | New amino-alkyl-amide derivatives as CCR3 receptor ligands | SANOFI-AVENTIS (FR) | 2008-11-27 | — | — | US | disclosed |
| EP-1300398-B1 | PROPANE-1,3-DIONE DERIVATIVES | ASTELLAS PHARMA INC (JP) | 2006-04-05 | — | — | EP | disclosed |
| US-20050267110-A1 | Propane-1, 3-dione derivative | YAMANOUCHI PHARMACEUTICAL CO., LTD. | 2005-12-01 | — | — | US | disclosed |
| US-6960591-B2 | Propane-1,3-dione derivative | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 2005-11-01 | — | — | US | disclosed |
| US-20030191164-A1 | Propane-1,3-dione derivatives | ASTELLAS PHARMA INC. (JP) | 2003-10-09 | — | — | US | disclosed |
| EP-1300398-A1 | PROPANE-1,3-DIONE DERIVATIVES | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 2003-04-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080293745-A1 | New amino-alkyl-amide derivatives as CCR3 receptor ligands | CCR3, CCR1, CCR4 | HDAC6 782/4885TDP1 4674/4885HSP90AA1 3789/4885 |
| US-20160237185-A1 | SYNTHESIS OF ACETAL COMPOUNDS | PAM, GNE, SAV1 | HDAC6 1095/4885TDP1 4759/4885HSP90AA1 4415/4885 |
| US-20030191164-A1 | Propane-1,3-dione derivatives | GNRHR, GPER1, FSHR | HDAC6 1694/4885TDP1 3390/4885HSP90AA1 3190/4885 |
| US-20050267110-A1 | Propane-1, 3-dione derivative | GNRHR, GPER1, FSHR | HDAC6 1803/4885TDP1 3371/4885HSP90AA1 3294/4885 |
| US-10738205-B2 | Polymerizable photoinitiators | PPOX, TPMT, MTHFD2 | HDAC6 4079/4885TDP1 551/4885HSP90AA1 2261/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.