SCHEMBL6027006

SCHEMBL6027006

CCOC(=O)CCCCOc1cccc(O)c1C=O

nearest known ligand 0.44

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 4/20 0.44
CYP4F2 P78329 1/20 0.42
CYP4A11 Q02928 1/20 0.42
CNR1 P21554 5/20 0.42
CNR2 P34972 5/20 0.42
PTPN1 P18031 2/20 0.41
CA12 O43570 1/20 0.41
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
CA7 P43166 1/20 0.41
CA9 Q16790 1/20 0.41
CA14 Q9ULX7 1/20 0.41
F2RL3 Q96RI0 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10926348 0.99 CNR1 (0.43) LTA4HCYP4F2CYP4A11CNR1CNR2
SCHEMBL11149449 0.87 ESR2 (0.44) LTA4HCYP4F2CYP4A11PTPN1
SCHEMBL10919678 0.86 ESR2 (0.43) LTA4HCYP4F2CYP4A11PTPN1F2RL3
SCHEMBL200763 0.84 TDP1 (0.46) LTA4HCYP4F2CYP4A11
SCHEMBL6027074 0.84 HTR1A (0.43) LTA4H
SCHEMBL12610480 0.84 CNR1 (0.47) CYP4F2CYP4A11CNR1CNR2CA12
SCHEMBL10918453 0.83 LTA4H (0.51) LTA4H
Velaresol SCHEMBL61907 0.82 PPARA (0.44) CNR1CNR2
SCHEMBL6026753 0.82 LMNA (0.42) CNR1CNR2PTPN1
SCHEMBL11382179 0.82 GAA (0.51) CNR1CNR2PTPN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7074770-B1 Method of DNA vaccination SMITHKLINE BEECHAM CORPORATION (US) 2006-07-11 US claimed
CN-1326358-A Method of DNA vaccination GLAXO GROUP LTD (GB) 2001-12-12 CN claimed
EP-1107785-A1 METHOD OF DNA VACCINATION GLAXO GROUP LIMITED (GB) 2001-06-20 EP claimed
WO-2000012121-A1 METHOD OF DNA VACCINATION GLAXO GROUP LIMITED (GB) 2000-03-09 WO claimed
US-4410537-A 3-HYDROXY-2-FORMYLPHENOXYPENTANOIC ACID DERIVATIVES BURROUGHTS WELLCOME CO. (US) 1983-10-18 US claimed
CN-110872228-A Compound of substituted phenol ether and intermediate and preparation method thereof 湖北普星特化学试剂有限公司 2020-03-10 CN disclosed
US-7074770-B1 Method of DNA vaccination SMITHKLINE BEECHAM CORPORATION (US) 2006-07-11 US disclosed
CN-1326358-A Method of DNA vaccination GLAXO GROUP LTD (GB) 2001-12-12 CN disclosed
EP-1107785-A1 METHOD OF DNA VACCINATION GLAXO GROUP LIMITED (GB) 2001-06-20 EP disclosed
WO-2000012121-A1 METHOD OF DNA VACCINATION GLAXO GROUP LIMITED (GB) 2000-03-09 WO disclosed
EP-0614357-A1 IMMUNOPOTENTIATORY AGENTS THE WELLCOME FOUNDATION LIMITED (GB) 1994-09-14 EP disclosed
WO-1994007479-A2 IMMUNOPOTENTIATORY AGENTS THE WELLCOME FOUNDATION LIMITED (GB) 1994-04-14 WO disclosed
US-4410537-A 3-HYDROXY-2-FORMYLPHENOXYPENTANOIC ACID DERIVATIVES BURROUGHTS WELLCOME CO. (US) 1983-10-18 US disclosed
EP-0022229-B1 SUBSTITUTED PHENOL ETHERS, THEIR PREPARATION, INTERMEDIATES THEREFOR, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THE PREPARATION THEREOF THE WELLCOME FOUNDATION LIMITED (GB) 1982-12-08 EP disclosed
EP-0022229-A1 Substituted phenol ethers, their preparation, intermediates therefor, pharmaceutical compositions containing them and the preparation thereof THE WELLCOME FOUNDATION LIMITED (GB) 1981-01-14 EP disclosed