⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7073998 | 0.86 | HTR6 (0.30) | — | |
| SCHEMBL60272 | 0.83 | HTR6 (0.33) | — | |
| SCHEMBL445165 | 0.80 | — | — | |
| SCHEMBL439955 | 0.79 | HTR2A (0.35) | — | |
| SCHEMBL216045 | 0.78 | SIGMAR1 (0.31) | — | |
| SCHEMBL437852 | 0.78 | HTR6 (0.33) | — | |
| SCHEMBL439185 | 0.78 | SIGMAR1 (0.32) | — | |
| SCHEMBL3380394 | 0.78 | HTR2A (0.35) | — | |
| SCHEMBL27454170 | 0.77 | — | — | |
| SCHEMBL441993 | 0.76 | SIGMAR1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6841634-B1 | Modified supported catalysts for the polymerization of olefins | BOREALIS TECHNOLOGY OY (FI) | 2005-01-11 | — | — | US | disclosed |
| US-6664352-B1 | Impregnating porous particulate support in mechanically fluidized state with catalyst material in mixer having horizontal axis counter-rotating interlocking mixing paddles | BOREALIS TECHNOLOGY OY (FI) | 2003-12-16 | — | — | US | disclosed |
| US-20030078340-A1 | Impregnating a mechanically fluidized porous particulate support material with a catalyst and polymerizing monomer(s) to produce polymer; heating mixture antioxidants, ultraviolet radiation stabilizer, diluent and metal stearate; depositing | BOREALIS TECHNOLOGY OY (FI) | 2003-04-24 | — | — | US | disclosed |
| US-5945367-A | Metallocenes with silyl-substituted bridges and their use for olefin polymerization | BOREALIS AG (AT) | 1999-08-31 | — | — | US | disclosed |