Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.40 |
| ▸ | TYR | P14679 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | USP5 | P45974 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.34 |
| ▸ | MGLL | Q99685 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL335853 | 0.86 | ADRB2 (0.48) | IDO1SMN1; SMN2LMNAHIF1AHPGD | |
| SCHEMBL6027579 | 0.83 | ACHE (0.47) | ESR1ESR2TAAR1SMN1; SMN2LMNA | |
| SCHEMBL335603 | 0.81 | POLB (0.37) | IDO1HTTTAAR1 | |
| SCHEMBL7122909 | 0.80 | PGR (0.39) | TYRHTTSMN1; SMN2RAB9AHPGD | |
| SCHEMBL335496 | 0.80 | TAAR1 (0.56) | HTTL3MBTL1TAAR1SMN1; SMN2LMNA | |
| SCHEMBL30502357 | 0.78 | HDAC4 (0.41) | TYRHTTTAAR1SMN1; SMN2LMNA | |
| SCHEMBL6912043 | 0.78 | ADRB2 (0.41) | SMN1; SMN2RAB9AALDH1A1 | |
| SCHEMBL4379785 | 0.75 | TAAR1 (0.50) | HTTTAAR1SMN1; SMN2LMNACYP2D6 | |
| SCHEMBL4379781 | 0.75 | TAAR1 (0.50) | HTTTAAR1SMN1; SMN2LMNACYP2D6 | |
| SCHEMBL6027209 | 0.74 | UGT2B7 (0.55) | CYP2D6HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7141527-B1 | Catalyst system and process for the polymerization of olefins | BASELL POLYOLEFINE GMBH (DE) | 2006-11-28 | — | — | US | disclosed |
| EP-1214364-B1 | CATALYST SYSTEM AND PROCESS FOR THE POLYMERIZATION OF OLEFINS | BASELL POLYOLEFINE GMBH (DE) | 2003-07-16 | — | — | EP | disclosed |
| EP-1214364-A1 | CATALYST SYSTEM AND PROCESS FOR THE POLYMERIZATION OF OLEFINS | Basell Technology Company B.V. (NL) | 2002-06-19 | — | — | EP | disclosed |
| WO-2001021674-A1 | CATALYST SYSTEM AND PROCESS FOR THE POLYMERIZATION OF OLEFINS | BASELL TECHNOLOGY COMPANY B.V. (NL) | 2001-03-29 | — | — | WO | disclosed |