Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LDHA | P00338 | 2/20 | 0.40 |
| ▸ | ESR1 | P03372 | 2/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.38 |
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.35 |
| ▸ | ALPI | P09923 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | XIAP | P98170 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | MMP8 | P22894 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | PTPRB | P23467 | 1/20 | 0.33 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | ALB | P02768 | 1/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
| ▸ | RARB | P10826 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9317096 | 0.84 | LDHA (0.52) | LDHAESR1ESR2MDM2SLC7A5 | |
| SCHEMBL5871840 | 0.79 | PTPRB (0.54) | LDHAESR1ESR2MMP8PTPRB | |
| SCHEMBL1896075 | 0.78 | MDM2 (0.61) | MDM2SLC7A5PTGS1ALPIPKM | |
| SCHEMBL5872055 | 0.77 | MMP8 (0.54) | LDHAPKMMMP8PTPRBNPC1 | |
| SCHEMBL3773871 | 0.77 | SLC6A2 (0.52) | LDHAESR1ESR2MDM2LMNA | |
| SCHEMBL27762682 | 0.77 | MDM2 (0.59) | MDM2SLC7A5PTGS1ALPIPKM | |
| SCHEMBL147865 | 0.77 | ALDH1A1 (0.48) | LDHAESR1ESR2MDM2SLC7A5 | |
| SCHEMBL2955193 | 0.77 | ESR1 (0.63) | LDHAESR1ESR2SLC7A5 | |
| SCHEMBL31635688 | 0.77 | ACACB (0.47) | LDHAESR1ESR2NPC1RAB9A | |
| SCHEMBL15454767 | 0.77 | MDM2 (0.59) | MDM2SLC7A5PTGS1ALPIPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7018786-B2 | Toning agents for use in thermographic recording materials | AGFA GEVAERT (BE) | 2006-03-28 | — | — | US | disclosed |
| US-20040152027-A1 | Toning agents for use in thermographic recording materials | AGFA-GEVAERT (BE) | 2004-08-05 | — | — | US | disclosed |
| EP-1435298-A2 | Toning agents for use in thermographic and photothermographic recording materials | Agfa-Gevaert (BE) | 2004-07-07 | — | — | EP | disclosed |